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Get a Prescription for Trelegy Online

Trelegy is typically prescribed to treat chronic obstructive pulmonary disease (COPD). Obtaining a Trelegy prescription online is simple; visit Your Doctors Online and connect with a doctor anytime, anywhere. Our online doctor will ask about your symptoms to determine treatment. Please know that a Trelegy refill will only be provided after a consultation with our doctor and if the medication is appropriate and safe.

What is Trelegy?

Trelegy is prescribed for managing chronic obstructive pulmonary disease (COPD) and consists of three active ingredients: fluticasone furoate, umeclidinium, and vilanterol. This drug belongs to the class of inhaled corticosteroids (ICS), long-acting beta-agonists (LABA), and long-acting muscarinic antagonists (LAMA). It is marketed under the brand name Trelegy Ellipta and is available as an inhalation powder.

Uses of Trelegy

Long-term treatment of COPD, including chronic bronchitis and emphysema, is possible with the help of the prescription drug Trelegy. Trelegy aids in the management of COPD by decreasing inflammation, relaxing airway muscles, and improving overall lung function. By reducing symptoms, preventing exacerbations, and streamlining treatment, this combination therapy for COPD patients improves their quality of life.

How does it work?

Trelegy is effective because it takes a holistic strategy by combining three active ingredients to tackle the intricacy of COPD. The first component, Fluticasone Furoate, is an inhaled corticosteroid (ICS), primarily reducing airway inflammation and promoting easier breathing.

Umeclidinium, a long-acting muscarinic antagonist (LAMA), reduces bronchoconstriction and increases airflow by relaxing the muscles surrounding the airways. Long-acting beta-agonists (LABAs) like vilanterol supplement the mechanism by relaxing airway muscles, resulting in more effortless and effective breathing. All of these work together to improve lung function and lessen the severity of COPD symptoms.

How to take Trelegy?

Trelegy is an inhalation powder generally administered once daily using the Ellipta inhaler device. You must take your medication exactly as directed by your doctor. It should be taken consistently at the same time daily, and the powder must be inhaled through the mouth. Trelegy should not be ingested orally.

Side effects of Trelegy

Commonly reported side effects of Trelegy include 

  • Upper respiratory tract infections
  • Headaches
  • Back pain
  • Pneumonia
  • Thrush

Rare but severe side effects may include: 

  • Heart rate
  • Allergic reactions
  • Alterations in blood pressure
  • Paradoxical bronchospasm
  • Worsened breathing
  • Osteoporosis with an increased risk of bone fractures

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Hi I’m dr. Nicole. How may I help you?

Dr. Nicole, I feel difficulty in breathing; I feel better after taking Trelegy. Can you give me a Trelegy refill?


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  • Trelegy one inhalation, once daily.




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Contraindications and precautions

  • Certain antifungal drugs, beta-blockers, and tricyclic antidepressants may interact negatively with Trelegy.
  • Trelegy should not be taken by anyone who has ever had an adverse reaction to fluticasone furoate, umeclidinium, or vilanterol.
  • Trelegy is not intended for treating acute bronchospasm but rather for treating chronic obstructive pulmonary disease. It should not be used as a rescue medication for sudden breathing difficulties.
  • Trelegy, like other medications containing long-acting beta2-adrenergic agonists (LABAs), may increase the risk of cardiovascular events. Patients with uncontrolled cardiovascular disorders should use caution.
  • Immunosuppression can occur after taking corticosteroids like the active ingredient in Trelegy, Fluticasone Furoate. Because of this, you might get sick more often.
  • The risk of developing cataracts and glaucoma may be raised by prolonged exposure to corticosteroids. It’s a good idea to get your eyes checked regularly.

FAQs About Trelegy

Is Trelegy a steroid?

Trelegy Ellipta contains Fluticasone, which is an inhaled corticosteroid (ICS). This corticosteroid component is included in the medication to help reduce inflammation in the airways.

How long does it take for Trelegy to work?

Some improvement in COPD symptoms can be observed within a few days to weeks of starting Trelegy. The onset of action may vary among individuals. It is essential to use it regularly for the best results.

Who should avoid Trelegy?

Trelegy should be avoided by individuals with known allergies to its components or severe hypersensitivity reactions to milk proteins. It is also not recommended for those taking another medication containing long-acting beta-agonists (LABA), individuals with heart issues, or those with bladder problems.

What are the Trelegy alternatives?

Alternative COPD treatments include other combination inhalers and individual medications such as Formoterol/Budesonide (Symbicort), Formoterol/Mometasone (Dulera), Salmeterol/Fluticasone (Advair Diskus), and Vilanterol/Fluticasone (Breo Ellipta).

Is it safe to take Trelegy with Prednisone?

No, there is a drug interaction between Prednisone and Trelegy however, that is a minor interaction. Taking Trelegy (Fluticasone, Umeclidinium, and Vilanterol) with prednisone should only be done under the supervision and guidance of a healthcare provider.

Can Trelegy cause hair loss?

No, hair loss is not a commonly reported side effect of Trelegy (Fluticasone, Umeclidinium, and Vilanterol). However, it’s important to note that individual reactions to medications can vary, and rare or unusual side effects can occur. If you experience hair loss while using Trelegy, it’s advisable to consult your healthcare provider.

How long does Trelegy stay in your system?

Trelegy’s duration of action is approximately 24 hours. However, how long Trelegy (Fluticasone, Umeclidinium, and Vilanterol) stays in your system can vary from person to person.

Can I take Trelegy with Albuterol?

Yes, Trelegy can be taken with albuterol. In fact, some healthcare providers may prescribe both medications to manage COPD or asthma symptoms effectively.

Can I take Trelegy every other day?

No, Trelegy should not be taken every other day unless specifically directed by your healthcare provider. It is typically prescribed as a once-daily medication for the long-term management of chronic obstructive pulmonary disease (COPD) and asthma.

Your Doctors Online uses high-quality and trustworthy sources to ensure content accuracy and reliability. We rely on peer-reviewed studies, academic research institutions and medical associations to provide up-to-date and evidence-based information to the users.

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