Skip the wait. Get a Nystatin prescription online for oral thrush, skin, yeast, and candida Infections in 5 minutes

Nystatin is prescription-only. You cannot buy it over the counter. Talk to a licensed online doctor and get a Nystatin (Nystop, Nyamyc) prescription in 5 minutes. New scripts and refills, $20/month flat, no insurance needed.

Get Nystatin oral suspension 100 000 units/ml online
Get Nystatin oral suspension 100 000 units/ml online

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Benefits of getting a Nystatin prescription from Your Doctors Online

Get treated for oral thrush or a yeast infection without the wait. Our seamless online care makes it easy to obtain a prescription so you can buy Nystatin from a pharmacy near you.

24/7 access

Our doctors are available 24/7, including nights, weekends, and holidays, so you can start treatment when you actually need it, not when the clinic opens.

Licensed doctors who manage dosing and treatment

Nystatin comes in different forms for different infections. A board-certified U.S. doctor confirms the infection, selects the appropriate formulation, and sets the course length to match the infection severity. Since Nystatin is prescription-only in the U.S., an online consult is often the fastest way to get it.

Choose any local pharmacy

Once approved, your prescription is sent to your pharmacy within minutes, ready for pickup the same day. You can choose any pharmacy near your town, and we’ll send your Nystatin prescription there.

$20/month flat fee, prescription included

Your subscription covers your consult, your nystatin prescription, any follow-up, doctor's notes, and lab orders if your doctor needs them. No per-visit fees. No charge for refills inside your subscription period.

How to get your Nystatin prescription and refill online

You can skip the office visit by talking to a doctor online through our telehealth app. You can choose to text, video, or audio chat and get your prescription without hassle within 5 minutes.

1

Start a consultation

Download our app, create an account, and share your infection symptoms to get started.

2

Speak to the doctor

Our licensed healthcare provider will review your symptoms via video, audio, or text chat to provide a diagnosis.

3

Get Nystatin online

If diagnosed with oral thrush, you will be prescribed Nystatin, and your online prescription will be sent to your local pharmacy.

What is Nystatin (Nystop, Nyamyc)?

Nystatin is an antifungal medicine used to treat yeast infections caused by Candida. It works by damaging the outer layer of the yeast, preventing it from growing and helping clear the infection.

Nystatin is sold under the brand names Nystop and Nyamyc. It comes as a liquid, cream, ointment, tablet, and powder to treat infections in the mouth, on the skin, and in the gut lining. Because it works only where it is applied and is not absorbed much into the bloodstream, it usually has few drug interactions and is often used in babies and during pregnancy. All forms of Nystatin require a prescription. There is no over-the-counter (OTC) Nystatin available.

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Drug Facts

Nystatin

Generic · Nystop, Nyamyc (brand)
FDA Approved
Generic Available
Tier 1
Drug class
Antifungal
Schedule
Not controlled
Requires Rx
Yes
Forms
Suspension · Cream · Ointment · Powder · Tablet
Strengths
100,000 units/mL–g · 500,000 units
Refillable
Yes

Conditions Nystatin treats

Our doctors prescribe Nystatin for yeast infections caused by Candida and similar fungi. The form prescribed depends on where the infection is located. Here are the conditions we treat most often.

Oral thrush

Skin yeast infections (cutaneous candidiasis)

Vaginal yeast infections

Diaper rash caused by yeast

Intestinal candidiasis

Severe sore throat with airway swelling

Lower-back pain with nerve-root inflammation

MS flares and severe psoriasis

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When to seek in-person care

Your doctor may recommend in-person care if you have a fever, spreading redness, trouble swallowing, severe pain, recurrent infections, or signs of a deeper fungal infection that may need stronger treatment, such as Fluconazole.

Who is eligible for an online Nystatin prescription?

Nystatin is prescription-only in the US. Our telehealth doctors can prescribe it online when you meet these criteria:

You are eligible if

Meet any criteria below

Adults and children with confirmed or suspected Candida infections of the mouth, skin, or vagina.
Patients on antibiotics, inhaled steroids, or chemotherapy who develop secondary oral or skin yeast infections.
Pregnant or breastfeeding patients, when topical/local Nystatin is preferred over systemic antifungals.

You are not eligible if

Discuss alternatives with a doctor

You are pregnant or breastfeeding.
You have an active fungal infection or severe untreated infection.
You are scheduled for a live vaccine in the next month.

How much does Nystatin cost without insurance?

Generic Nystatin oral suspension costs about $11 to $27 at major pharmacies, with the cash retail average around $26.91. Generic Nystatin cream costs about $11 to $25, with retail averaging $24.55. Brand-name Nystop powder retails around $180 per bottle. The other cost is the consultation, which is $20 per month for a Your Doctors Online subscription plan.

Consultation Plan
$20/month
Unlimited consults, refills, and doctor's notes. 24/7 availability.
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Cost with insurance

Plan Type Generic Nystatin Brand Nystop
Medicare Part D $0 – $10 $30 – $80+
Medicaid $0 – $4 Varies, often not covered
Comm. HMO/PPO $5 – $15 $30 – $80
ACA Plans $5 – $15 $30 – $80

Cost without insurance

Generic Nystatin Supply
$11 to $27
Walmart · Costco · Kroger Lowest
CVS · Walgreens Higher
Tip: Use a discount card (GoodRx, SingleCare, or RxSaver) at the counter to lower the price. With a GoodRx coupon, generic Nystatin is as low as $11.37.

Dosages and strengths of Nystatin

FormStrengthCommon use
Oral suspension100,000 units/mLOral thrush, intestinal candidiasis
Cream100,000 units/g (15 g, 30 g tubes)Skin yeast, diaper rash
Ointment100,000 units/gSkin yeast in dry, less weepy areas
Powder100,000 units/g (Nystop, Nyamyc)Skin fold yeast, moist areas, between toes
Tablets (oral)500,000 unitsIntestinal candidiasis
Oral suspension
Strength100,000 units/mL
Common useOral thrush, intestinal candidiasis
Cream
Strength100,000 units/g (15 g, 30 g tubes)
Common useSkin yeast, diaper rash
Ointment
Strength100,000 units/g
Common useSkin yeast in dry, less weepy areas
Powder
Strength100,000 units/g (Nystop, Nyamyc)
Common useSkin fold yeast, moist areas, between toes
Tablets (oral)
Strength500,000 units
Common useIntestinal candidiasis

Nystatin is FDA-approved in five forms. Your doctor will choose the strength and schedule based on the infection, your age, and its location.

Side effects of Nystatin

Most Nystatin side effects are mild because the drug is not absorbed into the bloodstream. It works only where you apply or swish it.

Common, mild effects

Nausea, vomiting, or mild stomach upset
Diarrhea, occasionally
Metallic or unpleasant taste in the mouth

Serious side effects (rare)

Severe allergic reaction (hives, swelling, trouble breathing)
Stevens-Johnson syndrome
Bronchospasm
Message a doctor

Contraindications and precautions

Most people tolerate Nystatin well because it is not absorbed from the gut or skin. Still, review these warnings before you start.

Do not use Nystatin if you have a known allergy to Nystatin or any ingredient in the formulation. Tell your doctor about all conditions before starting.

You have diabetes — the oral suspension contains sucrose, and a sugar-free formulation may be appropriate
You are pregnant or breastfeeding
You have a transplant and take cyclosporine — levels may change during co-administration
Your symptoms include trouble swallowing, persistent fever, or weight loss — these can signal esophageal candidiasis
Finish the entire course even if symptoms clear early — stopping too soon raises recurrence risk
Do not eat or drink for 30 minutes after each oral suspension dose

Our telehealth doctors prescribing Nystatin online

Frequently asked questions

No, Nystatin is a prescription-only medication. You cannot buy Nystatin at CVS, Walmart, Walgreens, or Amazon without a script, and there is no OTC online option. For skin yeast only, clotrimazole 1% cream and miconazole 2% cream are OTC alternatives. To get Nystatin, talk to a licensed online doctor and have your prescription sent to your pharmacy in 5 minutes.
Yes, swallow it. Swish 4–5 mL of Nystatin suspension in your mouth for 4–5 minutes, then swallow. Swallowing extends antifungal contact through the throat, where thrush is often most stubborn. Hold the suspension in your mouth as long as you can before swallowing.
Most people see improvement in 24–48 hours and full clearance in 7–14 days on the standard four-times-daily schedule. Finish the full course even if symptoms clear early to prevent recurrence.
Yes, you can take Nystatin and Fluconazole at the same time. Doctors sometimes prescribe both medicines together for more serious yeast infections in the mouth or esophagus when Nystatin alone is not enough. They work in different ways to kill yeast, so they can be used together. Nystatin mostly stays in the area where it is applied and does not enter the bloodstream much, so it usually does not cause important drug interactions.
For most people, no. Nystatin is not absorbed from the gut or skin, so it does not interact with common medications (warfarin, oral contraceptives, blood pressure pills, statins) the way many systemic antifungals do. The one documented concern is with cyclosporine in transplant patients. Tell your prescriber if you take cyclosporine.
Topical and vaginal forms of Nystatin are considered low-risk in pregnancy because they are not absorbed systemically from the GI tract or skin. However, oral forms are not safe during pregnancy. Always confirm with your prescribing doctor before taking Nystatin during pregnancy.
Yes, Nystatin vaginal tablets (100,000 units inserted once daily for 14 days per the FDA label) can be taken for vaginal yeast infections when the first-line treatment does not work for you. Most prescribers start with a single dose of oral fluconazole 150 mg or topical clotrimazole/miconazole as first-line. Nystatin is preferred when systemic exposure needs to be avoided.
No. Nystatin pastilles, formerly sold as Mycostatin Pastilles, have been discontinued in the US and are no longer commercially available. The prescription-only alternative in lozenge form is clotrimazole 10 mg troches (Mycelex Troche).
No, you should not take Nystatin for ringworm. Ringworm is caused by dermatophyte fungi (Trichophyton, Microsporum), not Candida. Nystatin has no activity against dermatophytes per the FDA label. Use clotrimazole 1% or terbinafine 1% topical OTC for ringworm.
If Nystatin has not helped improve your symptoms, return to your prescriber. They may switch you to systemic fluconazole, order a fungal culture (some Candida species, such as C. glabrata and C. krusei, are less susceptible to Nystatin), or check for an underlying cause, such as uncontrolled diabetes, recent antibiotics, or immune suppression. Do not double the dose on your own.

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