Skip the wait. Get a Nystatin prescription online for oral thrush, skin, yeast, and candida Infections in 5 minutes
Nystatin is prescription-only. You cannot buy it over the counter. Talk to a licensed online doctor and get a Nystatin (Nystop, Nyamyc) prescription in 5 minutes. New scripts and refills, $20/month flat, no insurance needed.
- Get new prescriptions and refills on your schedule
- Same-day pharmacy pickup
- Subscription starting from $20/month. Nystatin Rx plus unlimited consultations, lab orders, and doctor's notes
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Benefits of getting a Nystatin prescription from Your Doctors Online
Get treated for oral thrush or a yeast infection without the wait. Our seamless online care makes it easy to obtain a prescription so you can buy Nystatin from a pharmacy near you.
24/7 access
Our doctors are available 24/7, including nights, weekends, and holidays, so you can start treatment when you actually need it, not when the clinic opens.
Licensed doctors who manage dosing and treatment
Nystatin comes in different forms for different infections. A board-certified U.S. doctor confirms the infection, selects the appropriate formulation, and sets the course length to match the infection severity. Since Nystatin is prescription-only in the U.S., an online consult is often the fastest way to get it.
Choose any local pharmacy
Once approved, your prescription is sent to your pharmacy within minutes, ready for pickup the same day. You can choose any pharmacy near your town, and we’ll send your Nystatin prescription there.
$20/month flat fee, prescription included
Your subscription covers your consult, your nystatin prescription, any follow-up, doctor's notes, and lab orders if your doctor needs them. No per-visit fees. No charge for refills inside your subscription period.
How to get your Nystatin prescription and refill online
You can skip the office visit by talking to a doctor online through our telehealth app. You can choose to text, video, or audio chat with the doctor. The licensed U.S. doctor confirms the Candida infection and picks the right form , oral suspension, cream, ointment, or powder, then sends your prescription to your pharmacy for same-day pickup.
Start a consultation
Download our app, create an account, and share your infection symptoms to get started.
Speak to the doctor
Our licensed healthcare provider will review your symptoms via video, audio, or text chat to provide a diagnosis.
Get Nystatin online
If the doctor confirms a Candida infection of the mouth, skin, or vagina, they select the form that matches it and send your prescription to your local pharmacy.
What is Nystatin (Nystop, Nyamyc)?
Nystatin is an antifungal medicine used to treat yeast infections caused by Candida. It works by damaging the outer layer of the yeast, preventing it from growing and helping clear the infection.
Nystatin is sold under the brand names Nystop and Nyamyc. It comes as a liquid, cream, ointment, tablet, and powder to treat infections in the mouth, on the skin, and in the gut lining. Because it works only where it is applied and is not absorbed much into the bloodstream, it usually has few drug interactions and is often used in babies and during pregnancy. All forms of Nystatin require a prescription. There is no over-the-counter (OTC) Nystatin available.
Get Nystatin prescription nowNystatin
Generic · Nystop, Nyamyc (brand)Conditions Nystatin treats
Our doctors prescribe Nystatin for yeast infections caused by Candida and similar fungi. The form prescribed depends on where the infection is located. Here are the conditions we treat most often.
Oral thrush
Skin yeast infections (cutaneous candidiasis)
Vaginal yeast infections
Diaper rash caused by yeast
Intestinal candidiasis
When to seek in-person care
Your doctor may recommend in-person care if you have a fever, spreading redness, trouble swallowing, severe pain, recurrent infections, or signs of a deeper fungal infection that may need stronger treatment, such as Fluconazole.
How much does Nystatin cost without insurance?
Generic Nystatin oral suspension costs about $11 to $27 at major pharmacies, with the cash retail average around $26.91. Generic Nystatin cream costs about $11 to $25, with retail averaging $24.55. Brand-name Nystop powder retails around $180 per bottle. The other cost is the consultation, which is $20 per month for a Your Doctors Online subscription plan.
Cost with insurance
| Plan Type | Generic Nystatin | Brand Nystop |
|---|---|---|
| Medicare Part D | $0 – $10 | $30 – $80+ |
| Medicaid | $0 – $4 | Varies, often not covered |
| Comm. HMO/PPO | $5 – $15 | $30 – $80 |
| ACA Plans | $5 – $15 | $30 – $80 |
Cost without insurance
Dosages and strengths of Nystatin
| Form | Strength | Common use |
|---|---|---|
| Oral suspension | 100,000 units/mL | Oral thrush, intestinal candidiasis |
| Cream | 100,000 units/g (15 g, 30 g tubes) | Skin yeast, diaper rash |
| Ointment | 100,000 units/g | Skin yeast in dry, less weepy areas |
| Powder | 100,000 units/g (Nystop, Nyamyc) | Skin fold yeast, moist areas, between toes |
| Tablets (oral) | 500,000 units | Intestinal candidiasis |
Nystatin is FDA-approved in five forms. Your doctor will choose the strength and schedule based on the infection, your age, and its location.
Side effects of Nystatin
Most Nystatin side effects are mild because the drug is not absorbed into the bloodstream. It works only where you apply or swish it.
Common, mild effects
Serious side effects (rare)
Contraindications and precautions
Most people tolerate Nystatin well because it is not absorbed from the gut or skin. Still, three groups of warnings matter before you start.
Do not use Nystatin if you have a known allergy to Nystatin or any ingredient in the formulation.
Tell your doctor before starting Nystatin if:
While taking Nystatin:
Our telehealth doctors prescribing Nystatin online
Dr. Richard Honaker is a board-certified physician with more than 40 years of experience in family and emergency medicine. He serves as Chief Medical Advisor at Your Doctors Online and is affiliated with Medical City Plano in Texas. Recognized multiple times by D Magazine and Texas Monthly, Dr. Honaker provides evidence-based care across a wide range of conditions including diabetes, hypertension, and injury care.
Dr. Monique Rainford is an OB/GYN expert and Assistant Clinical Professor at Yale School of Medicine. With 25+ years of experience, she’s led OB/GYN departments at Yale Health and Baltimore Medical System. Her clinical interests include pregnancy, menstrual health, chronic pelvic conditions, and lifestyle medicine. Dr. Rainford advocates for maternal health equity, especially in underserved communities.
Dr. Candice Fraser is an OB/GYN practitioner and founder of Trinity Medical Care. With over a decade of experience, she focuses on reproductive care, menstrual health, and menopause management. Along with medical training and residency, she also holds an MBA in healthcare management, blending business insight with clinical excellence.
Frequently asked questions
Can I buy Nystatin over the counter, online, or without a prescription?
No, Nystatin is a prescription-only medication. You cannot buy Nystatin at CVS, Walmart, Walgreens, or Amazon without a script, and there is no OTC online option. For skin yeast only, clotrimazole 1% cream and miconazole 2% cream are OTC alternatives. To get Nystatin, talk to a licensed online doctor and have your prescription sent to your pharmacy in 5 minutes.
Do you swallow Nystatin oral suspension or spit it out?
Swallow it. Swish 4–5 mL of Nystatin suspension in your mouth for 4–5 minutes, then swallow. Swallowing extends antifungal contact through the throat, where thrush is often most stubborn.
How long does it take Nystatin to work for oral thrush?
Most people see improvement in 24–48 hours and full clearance in 7–14 days on the standard four-times-daily schedule. Finish the full course even if symptoms clear early to prevent recurrence.
Can I take Nystatin and Fluconazole at the same time?
Yes, you can take Nystatin and Fluconazole at the same time. Doctors sometimes prescribe both medicines together for more serious yeast infections in the mouth or esophagus when Nystatin alone is not enough. They work in different ways to kill yeast, so they can be used together. Nystatin mostly stays in the area where it is applied and does not enter the bloodstream much, so it usually does not cause important drug interactions.
Are there drugs I should avoid while taking Nystatin?
For most people, no. Nystatin is not absorbed from the gut or skin, so it does not interact with common medications (warfarin, oral contraceptives, blood pressure pills, statins) the way many systemic antifungals do. The one documented concern is with cyclosporine in transplant patients. Tell your prescriber if you take cyclosporine.
Is Nystatin oral suspension safe during pregnancy?
Topical and vaginal forms of Nystatin are considered low-risk in pregnancy because they are not absorbed systemically from the GI tract or skin. However, oral forms are not safe during pregnancy. Always confirm with your prescribing doctor before taking Nystatin during pregnancy.
Can Nystatin be used for vaginal yeast infections?
Yes, Nystatin vaginal tablets (100,000 units inserted once daily for 14 days per the FDA label) can be taken for vaginal yeast infections when the first-line treatment does not work for you. Most prescribers start with a single dose of oral fluconazole 150 mg or topical clotrimazole/miconazole as first-line. Nystatin is preferred when systemic exposure needs to be avoided.
Are Nystatin lozenges available in the US in 2026?
No. Nystatin pastilles, formerly sold as Mycostatin Pastilles, have been discontinued in the US and are no longer commercially available. The prescription-only alternative in lozenge form is clotrimazole 10 mg troches (Mycelex Troche).
Can I take Nystatin for ringworm?
No, you should not take Nystatin for ringworm. Ringworm is caused by dermatophyte fungi (Trichophyton, Microsporum), not Candida. Nystatin has no activity against dermatophytes per the FDA label. Use clotrimazole 1% or terbinafine 1% topical OTC for ringworm.
What if Nystatin does not work after 7 days?
If Nystatin has not helped improve your symptoms, return to your prescriber. They may switch you to systemic fluconazole, order a fungal culture (some Candida species, such as C. glabrata and C. krusei, are less susceptible to Nystatin), or check for an underlying cause, such as uncontrolled diabetes, recent antibiotics, or immune suppression. Do not double the dose on your own.
