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Get Tizanidine (Zanaflex) Prescription Refill Online

Tizanidine is used for muscle spasms that are usually associated with multiple sclerosis and brain or spinal injury. If you have these conditions, you can get refill Tizanidine online. Obtaining a Tizanidine prescription online is simple; visit Your Doctors Online and connect with a doctor anytime, anywhere. Our online doctor will ask about your symptoms to determine your treatment plan. They may suggest a follow-up appointment or clinic visit.

Please know that a Tizanidine refill will only be provided after a consultation with our doctor and if the medication is appropriate and safe.

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Hi I’m dr. Nicole. How may I help you?

Dr. Nicole, I have been taking Tizanidine before and ran out of it. Can you give me a Tizanidine refill?


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  • Tizanidine 2 mg tablet
  • Take one tablet thrice daily


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What is Tizanidine and how to take it

What is Tizanidine (Zanaflex)?

Muscle spasms caused by a brain or spinal cord injury or by multiple sclerosis can be treated with tizanidine, a skeletal muscle relaxant. It is a skeletal muscle relaxant available in the market under the brand names Zanaflex, Zanaflex capsule, and Comfort Pac WTizanidine. Other drugs from the same therapeutic class include Baclofen, Diazepam, Robaxin, Cyclobenzaprine, Methocarbamol, and Soma.

How does it work?

Tizanidine works by allowing the muscles to relax, which slows down the action in the brain and nervous system. Tizanidine is a skeletal muscle relaxant with a central action that affects spinal polysynaptic reflexes. It activates adrenergic alpha 2 receptors which impairs the release of excitatory amino acids, spinal interneurons, glutamate, and aspartate. Tizanidine is available as injections, tablets, capsules, and oral suspensions.

How to take Tizanidine?

It is recommended to take 2mg Tizanidine every six to eight hours. Take the tablet with a glass full of water with or without food. Avoid crushing or chewing the tablet, and do not stop taking it abruptly. It is recommended to withdraw slowly from the medication as it can cause withdrawal symptoms such as anxiety, fast heart rate, tremors, and high blood pressure.

Important information about Tizanidine

Tizanidine is a skeletal muscle relaxant drug. You will require a prescription for Tizanidine. Here are some essential points that you should know about this drug:

  • Some common side effects of Tizanidine may include dry mouth, dizziness, nervousness, vomiting, constipation, tingling, stomach pain, increased muscle spasms, rash, flu-like symptoms, trouble speaking, drowsiness, weakness, depression, vomiting, and back pain. Speak to your doctor if you observe any of these symptoms persistently.
  • Serious side effects of Tizanidine may include chest pain, discomfort, nausea, pain, unusual tiredness, weak or shallow breathing, lightheadedness, pain or burning, allergic reactions, fever, chills, nervousness, fatigue, weak or shallow breathing, pain or burning when you urinate.
  • Tizanidine is contraindicated if you have hypersensitivity to any of its ingredients. It is also contraindicated with some medications such as Adagrasib, Alprazolam, Benzhydrocodone, Buprenorphine, Butorphanol, Cetrizine, Codeine, Diazepam, Diphenhydramine, Fentanyl, Hydrocodone,  

Levorphanol, Meclizine, Methanol, Oxycodone, Tramadol, and more. Inform your doctor about all the medications you are currently taking prior to commencing treatment with Tizanidine.

FAQs About Tizanidine

Can online doctors prescribe muscle relaxers?

You can get a Tizanidine refill online form one of our qualified professionals via the Your Doctors Online app.

How long it takes for Tizanidine (Zanaflex) to work?

Tizanidine starts working best within one to two hours of intake, and it lasts for three to six hours. The peak plasma concentration of Tizanidine is within 1.5 hours of intake.

How much Tizanidine (Zanaflex) can I take for anxiety?

Tizanidine is not usually recommended for anxiety. It is usually prescribed for muscle spasms due to multiple sclerosis. However, if you have been prescribed Tizanidine for anxiety, follow the exact dosing schedule as your doctor recommended.

How much Tizanidine (Zanaflex) can I take at once?

It is recommended to take Tizanidine every six to eight hours, 2 mg each time. The maximum daily dose of Tizanidine should not exceed 36 mg.

How can I refill my Zanaflex (Tizanidine) prescription?

You can get a Zanaflex refill online by consulting one of our qualified healthcare professionals online via our app, Your Doctors Online.

What should you not take Zanaflex (Tizanidine) with?

Tizanidine is strictly contraindicated if you are taking Ciprofloxacin, Opioids, and Fluvoxamine. Share the detailed list of medications that you are taking with your health care provider to avoid any potential contraindications.

Does Zanaflex (Tzanidine) relax muscles?

Yes, it is a centrally acting skeletal muscle relaxant used to alleviate spasms caused by conditions like multiple sclerosis or neurological trauma.

When is the best time to take Zanaflex?

Zanaflex is usually recommended to take thrice daily at a dosing interval of 6 to 8 hours each. Therefore it should be taken in the morning, noon, and evening. However, your doctor may recommend specific dose timings based on your individual needs.

Who should not take Zanaflex?

Tizanidine should be avoided if you are hypersensitive to Zanaflex or any of its ingredients. It is also contraindicated for use if you are taking Ciprofloxacin and Fluvoxamine.

What happens if I miss a dose of Zanaflex?

You can take the dose as soon as you remember however, do not double dose on Zanaflex if you have missed a dose and it is time to take your next dose.

What happens if I take too much Zanaflex?

If you overdose on Zanflex, it may be life-threatening or lead to side effects such as altered mental status, hypotension, bradycardia, and respiratory depression.

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