Skip the wait. Get an online Prednisone prescription within 5 minutes

Prednisone is a corticosteroid that treats inflammation, severe allergic reactions, asthma flares, and autoimmune conditions. Talk to a licensed doctor from home. If Prednisone is right for you, your prescription is sent to your pharmacy for same-day pickup.

Subscription starting from $20/month.

Includes unlimited consultations, prescriptions, and a doctor’s note

Get prednisone prescriptions and refill online in the US and Canada

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Benefits of getting your Prednisone prescription from Your Doctors Online

Choosing our telehealth service for your Prednisone needs means you’ll benefit from a faster, more convenient healthcare experience.

24/7 access when a flare hits

A prednisone-worthy flare (asthma attack, severe allergic reaction, poison ivy, gout) usually starts at the wrong time. Our doctors are available 24/7, including nights, weekends, and holidays, so you can start treatment when you actually need it, not when the clinic opens on Monday.

Licensed doctors who handle dosing and tapering

Prednisone is not a one-size-fits-all medication. Your dose depends on the condition, the severity, your other medications, and how your body responds. Every consultation is with a board-certified U.S doctor. They pick the right dose and write a step-down taper for any course longer than two weeks.

Care that understands travel-related infections

Your e-prescription is sent to the pharmacy of your choice within minutes of your consultation. Real-time tracking shows when the pharmacy receives, processes, and fills it. Most patients pick up their prednisone the same day.

$20/month flat fee, prescription included

Your subscription covers your consult, your prednisone prescription, any follow-up, doctor's notes, and lab orders if your doctor needs them. No per-visit fees. No charge for refills inside your subscription period.

How to get a Prednisone prescription online?

Getting your Prednisone through an online doctor is simple. Here’s how the process works:

1

Start Your Consultation

Create an account, share your medical history and symptoms of an asthma flareup, allergic reaction, and rheumatoid arthritis to get connected to an online doctor.

2

Meet a licensed provider

Your doctor will review your medical history via video, audio, or text chat to assess the severity and underlying cause of your symptoms.

3

Receive Prednisone

If you’re diagnosed with an inflammatory condition, such as rheumatoid arthritis, Crohn’s disease, or a severe allergic reaction, your doctor will authorize the appropriate prednisone dose.

What is Prednisone?

Prednisone is a corticosteroid that mimics the hormone your adrenal glands naturally produce to control inflammation. When your body is fighting an injury, infection, or autoimmune flare, your immune system can dial up inflammation more than you actually need.

Prednisone calms that response, which reduces swelling, redness, and pain. It is sold under the brand name Rayos and in a generic form.

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Drug Facts

Prednisone

Generic · Rayos (brand)
FDA Approved
Generic Available
Tier 1
Drug class
Corticosteroid
Schedule
Not controlled
Requires Rx
Yes
Forms
Tablet · Oral solution
Strengths
1 mg – 50 mg
Refillable
Yes

Who is eligible for an online Prednisone prescription?

Prednisone is prescription-only in the US. Our telehealth doctors can prescribe it online when you meet these criteria:

You are eligible if

Meet any criteria below

You already have a prescription and need a refill.
You have a confirmed inflammatory or autoimmune condition.
You have a severe allergic reaction or hives not responding to antihistamines.
You have poison ivy that is spreading or blistering.
You are 18 or older (or joining with a guardian).

You are not eligible if

Discuss alternatives with a doctor

You are pregnant or breastfeeding.
You have an active fungal infection or severe untreated infection.
You are scheduled for a live vaccine in the next month.

How much does Prednisone cost?

Generic prednisone is extremely affordable. While brand-name options like Rayos are expensive, our subscription service ensures you have affordable access to board-certified medical care and prescriptions.

Consultation Plan
$20/month
Unlimited consults, refills, and doctor's notes. 24/7 availability.
Start subscription

Cost with insurance

Plan Type Generic Rayos
Medicare Part D $0 – $10 $30+
Medicaid $0 – $4 Varies
Comm. HMO/PPO $5 – $15 $30 – $80
ACA Plans $5 – $15 $30 – $80

Cost without insurance

30-Tablet Generic Supply
$4 to $12
Walmart · Costco · Kroger Lowest
CVS · Walgreens Higher
Tip: Use a discount card like GoodRx at the counter to secure these lowest cash prices.

Conditions that Prednisone can treat

Our doctors prescribe prednisone for short-term flares where inflammation is the underlying issue.

Asthma flares

Severe allergic reactions and hives

Rheumatoid arthritis and autoimmune flares

Acute gout

Lingering cough after infection

Severe sore throat with airway swelling

Lower-back pain with nerve-root inflammation

MS flares and severe psoriasis

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Go to the ER instead

Go to an ER if diagnosed with Stevens-Johnson syndrome, anaphylaxis, or severe asthma needing a nebulizer.

Strengths and dosages of Prednisone

Available in 5 mg to 60 mg. Your doctor will pick the lowest dose that controls symptoms and may use a taper schedule for courses longer than two weeks.

Immediate-release tablets

Most prescribed form
Available Strengths
1 mg
2.5 mg
5 mg
10 mg
20 mg
50 mg

Oral solution

Liquid alternative
Concentration
5 mg / 5 mL
Per Dose

Important: Always take exactly as prescribed; do not stop suddenly.

Side effects of Prednisone

Most people on a short course see only mild side effects. Higher doses or longer courses make noticeable effects more likely.

Common, mild effects

Trouble sleeping (if taken in evening)
Mood shifts or irritability
Increased appetite or fluid retention

Less common, more serious

Increased risk of infections
Higher blood sugar levels
Worsening of high blood pressure
Message a doctor

Contraindications and precautions

A safety checklist your doctor will walk through with you before starting treatment.

Do not discontinue Prednisone abruptly, especially after more than two weeks. Always taper your dosage exactly as your doctor instructs to avoid withdrawal effects.

Do not take Prednisone if you have a known allergy to it or any ingredient
Avoid Prednisone if you have systemic fungal infections
Inform your doctor of any bacterial or viral infection
Take under doctor supervision if you have diabetes
Monitor your blood pressure during treatment
Adjust dose if you have kidney or liver disease

Our telehealth doctors prescribing Prednisone

Frequently asked questions

No, Prednisone is a prescription-only corticosteroid in the United States. It is not stocked over the counter at any major pharmacy, including CVS, Walgreens, Walmart, Kroger, or Costco. Sites that claim to sell Prednisone online without a prescription are operating outside FDA regulation. The fastest legal route is a 5-minute telehealth consultation on Your Doctors Online. A licensed doctor reviews your case and, if appropriate, sends an online prescription to your local pharmacy.

Yes, getting a prednisone prescription through a HIPAA-compliant telehealth platform like Your Doctors Online is legal in the United States under the Ryan Haight Online Pharmacy Consumer Protection Act. Because Prednisone is not a controlled substance, board-certified physicians can prescribe it through a telehealth consultation after a proper evaluation.

In less than an hour through Your Doctors Online. Sign in or create your account, start a consult, talk to a US-licensed doctor over chat, video, or audio, and your prescription is sent to your chosen pharmacy in less than an hour, if Prednisone is right for you.

Prednisone is not addictive in the way drugs of abuse are. Your body can develop a physiological dependence on longer courses, though, because external Prednisone tells your adrenal glands to slow their own cortisol production. That is why your doctor will taper you off slowly rather than letting you stop suddenly. Stopping abruptly after a long course can cause fatigue, weakness, body aches, and (rarely) adrenal crisis.

Here are a few things you should keep in mind when starting your Prednisone prescription:

  1. Avoid combining prednisone with NSAIDs (ibuprofen, naproxen, meloxicam) when you can. 
  2. Do not get a live vaccine (MMR, varicella, yellow fever, intranasal flu) during your course or for one month after it ends. During this time, prednisone suppresses your immune response, so live vaccines could make you sick. 
  3. Limit alcohol intake, as it can irritate your stomach lining.
  4. Do not stop Prednisone abruptly if you have been taking it for more than two weeks. Always taper as your doctor instructs.

Yes, if your condition is stable. Your doctor will run a brief consultation to confirm your current dose, your indication, and whether you have had any new symptoms. Bring your original prescriber’s name, the strength, and your pharmacy info to the consult. If your condition has changed or you have not seen a doctor in over a year, your provider may ask for additional information.

For an acute gout attack, doctors usually prescribe 30–40 mg of prednisone daily until symptoms improve (typically 2–5 days), then a gradual taper over 7–10 days. This is often used as an alternative to Colchicine or NSAIDs when those are not options for you. Your dose may be adjusted based on your individual case.

Dosing varies by provider and severity. A common approach is 40–60 mg on day 1, decreasing by 10–20 mg every 1–2 days. Some doctors prescribe a fixed dose for 5 days without a taper, as short courses generally don’t require one. Your doctor will determine the right dose for your specific case. One example of a 5-day prednisone taper for acute back pain is as follows:

  • 40–60 mg on day 1
  • 60 mg on day 1
  • 40 mg on day 2
  • 40 mg on day 3
  • 20 mg on day 4
  • 20 mg on day 5

Get your prescription now

Talk to a licensed doctor about your Prednisone prescription