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Get a prescription refill for Methylprednisolone (Medrol) online

Methylprednisolone belongs to the drug class of glucocorticoid, which is prescribed for medical conditions like arthritis, blood disorders, severe allergic reactions, skin diseases, kidney disorders, asthma, and immune system disorders.

Obtaining a Methylprednisolone (Medrol) prescription refill online is simple; visit Your Doctors Online and connect with a doctor anytime, anywhere. Our online doctor will ask about your symptoms to determine treatment. 

What is Methylprednisolone (Medrol)?

Methylprednisolone (Medrol) is a type of a steroid called glucocorticoid prescribed to treat a number of allergic conditions, asthma, IBD and arthritis The brand name Medrol is commonly used to refer to the medication Methylprednisolone. Other corticosteroids in the same class include prednisone, prednisolone, dexamethasone, and hydrocortisone.

What are the uses of Methylprednisolone?

Some of the most prominent uses of methylprednisolone are: 

  • Treatment and management of inflammatory conditions e.g. lupus, arthritis.
  • Treating the allergy symptoms 
  • Treating and managing asthma symptoms 
  • Management of severe skin conditions like psoriasis 
  • Treatment and prevention of organ transplant rejection symptoms 

What are the different dosage forms and strengths of Methylprednisolone?

Methylprednisolone comes in 3 different dosage forms 

  • Oral tablets ( 2 mg,4 mg,8 mg,16 mg,32 mg)
  • Injectables (40 mg/mL,125 mg/mL,500 mg/vial,1 g/vial)
  • Oral suspension (5 mg/5 mL)

The right and most suited dosage form can only be determined by your healthcare provider after the careful and detailed diagnosis.

How to take it?

Methylprednisolone tablets can typically be taken with a full glass of water. It’s advisable to follow the specific instructions provided by your healthcare provider. If the medication causes stomach upset, your doctor may suggest taking it with food or milk.

How does it work?

Methylprednisolone works by imitating the effects of naturally occurring corticosteroid hormones that are produced by the adrenal glands in the body. It also reduces inflammation and suppresses the immune system by reducing the activity of inflammatory molecules and stopping immune cells from damaging healthy tissue. This treatment helps in reducing symptoms related to arthritis and other inflammatory conditions effectively.

What are the side effects of Methylprednisolone?

Some of the most common side effects of methylprednisolone: 

  • Increased appetite
  • Weight gain
  • Insomnia
  • Mood changes (e.g, irritability, anxiety)
  • Increased blood sugar levels

While other severe side effects: 

  • Osteoporosis
  • Increased risk of infections
  • Peptic ulcers
  • High blood pressure
  • Cataracts or glaucoma
  • Severe allergic reactions (e.g anaphylaxis)

Request Methylprednisolone prescription online

Get an online prescription for Methylprednisolone in three easy steps.


Describe your issue

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  • Arthritis
  • Anemia
  • STD
  • UTI
  • Infections
  • Covid


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Hi I’m Dr. Nicole. How may I help you?

Dr. Nicole, I have been taking Methylprednisolone for arthritis. Can you give me a Medrol refill?


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  • Methylprednisolone (Medrol) 24 mg tablet
  • Take one tablet once daily.


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Precautions and contraindications

  • Before taking any prescription medication consult your doctor to discuss your medication and medical condition history for effective prescription. 
  • Discuss in case of any allergy history due to any medication to get the well suited prescription that suits your needs. 
  • This medication is generally not recommended for pregnant it might cause harm to the developing baby. 

FAQs about Methylprednisolone (Medrol)

How long does it take for Methylprednisolone to work?

It is absorbed quickly into your system following your first dose within 1-2 hrs. So it starts working soon after oral administration within a few hours. If you notice anything unusual after oral administration, you can always talk to your doctor.

Can you take Celebrex with Methylprednisolone?

No, it is recommended not to take Celebrex (Celecoxib) with Methylprednisolone because this combination may have adverse effects such as increased risk of side effects such as gastric inflammation, bleeding, and more.

Is Medrol dose packed over the counter?

Medrol dose packs containing Methylprednisolone are not available for use over the counter. You will require a prescription to obtain Medrol. You can get a Methylprednisolone refill online by connecting with one of our qualified doctors online.

What to avoid while taking Methylprednisolone?

Methylprednisolone can weaken your immune system, so avoid contact with people who have viral or bacterial infections because you are susceptible to infectious diseases due to a weakened immune system. Avoid taking alcohol, grapefruit, and smoking while taking methylprednisolone. You should also avoid taking any herbal supplements, vitamins, or other prescription or over-the-counter medications without discussing them with your doctor.

How long does Methylprednisolone stay in your system?

Methylprednisolone stays in your system for about twelve to thirteen hours after oral administration. You can discuss with one of our doctors online via our app if you have any questions about Methylprednisolone.

Does Methylprednisolone make you sleepy?

Methylprednisolone does not generally makes you sleepy, as drowsiness is not one of its side effects, however, you can discuss it with your doctor if you notice any unusual side effects.

How long do medrol side effects last?

Usually the side effects of medrol subsides in 24-48 hours after the drug is cleared out and left the body. All the minor side effects can be felt till the medication stays in your system for the treatment of medical conditions.

Can you take Benzonatate with Methylprednisolone?

Yes, you can take benzonatate with Methylprednisolone. There are no known or significant side effects of benzonatate with methylprednisolone. However, it's important to consult your doctor or pharmacist before combining any medication for an effective dosage regimen.

Can you drink alcohol while taking Methylprednisolone?

No, it is not advisable to take alcohol with Methylprednisolone as it may cause serious gastric issues and lead to side effects such as gastric bleeding, dizziness, and drinking alcohol.

What is the difference between Prednisone and Methylprednisolone?

Methylprednisolone is slightly stronger than Prednisone; if we look into the dosage strengths comparison, Methylprednisolone is effective at 4mg, and Prednisone is effective at 5mg.

How many days can Medrol be taken?

Medrol is not prescribed for long durations it is typically recommended to take it for 4-6 days, but you should follow your doctor’s recommendation as the exact dosage and duration may vary depending on your individual condition.

Who should not take Medrol?

You should not take Medrol if you have known hypersensitivity to Methylprednisolone or any of its ingredients. You should also avoid taking Medrol if you have systemic fungal infections. Medrol is also prohibited in people who have taken vaccines of live attenuated viruses because Medrol suppresses the immune system, and the person can easily get infected. It is also recommended to avoid Medrol during pregnancy or breastfeeding.

What happens if I take too much Medrol?

If you take too much Medrol, you may experience heightened side effects, including stomach pain, confusion, urination, and weakness. You should seek medical attention immediately if you think you have overdosed on Medrol.

What happens if I miss a dose of Medrol?

Methylprednisolone should be taken as soon as remembered if a dose was missed. If you miss a dose and think it might be close to the time for your next dose, don't take two. If you suspect that incorrect dosing is the cause of any unusual symptoms, you should contact your healthcare provider immediately.

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