How does Prednisone work for sinus infection?

Prednisone for sinus infection
Medically reviewed by Dr. Asim Cheema

Key Takeaways

  • Sinus infection, also called sinusitis, is an infection that comprises nasal congestion, pressure, and excessive mucus production.
  • Prednisone, an oral steroid, may be prescribed for some sinus infections. However, research shows that it may be best left for severe cases. If your sinus infection is mild, prednisone may not make you feel better faster, and its side effects and risks will likely outweigh any possible benefits.
  • Some common side effects of taking prednisone can be weight gain, increased appetite, insomnia, and mood changes. It’s not an OTC medication and can only be prescribed by a healthcare provider. 
  • It’s beneficial to only follow the prescribed dose of prednisone for the specified period to avoid any unwanted side effects. 

Overview

Sinus infections, either acute or chronic, can cause extreme irritation, discomfort, inflammation, and shortness of breath. Treatment options for sinus infections start with home remedies and antibiotics, which can help relieve sinus infection, inflammation, and irritation by treating the infection. Healthcare providers also prescribe prednisone for effective treatment. Prednisone is a corticosteroid that treats the infection due to its anti-inflammatory and immunosuppressive properties. 

Sinus infections, if left untreated, can cause nasal congestion, thick nasal discharge, and facial pressure. Treat it before it gets worse!

Can prednisone treat a sinus infection?

Yes, Prednisone can treat prolonged sinus infections if prescribed by a healthcare provider after a thorough consultation. It is an anti-inflammatory and immunosuppressive drug prescribed for sometimes acute and chronic sinus infections, depending on the nature and severity of an infection. It is also prescribed for conditions like IBD, arthritis, and skin conditions like psoriasis and eczema) and autoimmune disorders, e.g., multiple sclerosis, COPD, and bronchitis

How does prednisone work for sinusitis?

Prednisone is considered a short-term treatment option for sinusitis to relieve inflammatory symptoms. It works best for sinusitis by taking over the body’s inflammatory response. When polyps are formed in the body due to sinusitis, it reduces the size of polyps and improves symptoms. 

Prednisone is often considered for treating sinus infections when other antibiotics take longer to relieve and improve symptoms. It also effectively relieves pressure and congestion. 

Always follow the dosing regimen and instructions prescribed by your healthcare provider to avoid any unwanted side effects of the corticosteroids

Prednisone dosage for sinus infections

Dose for adults:

A common dose for adults with severe sinus infections is 20 to 40 mg daily, usually split into a single or divided dose for a short period, such as 5 to 10 days, to reduce inflammation.

Dose for Children: 

The dosage for children is based on body weight and ranges from 0.5 to 2 mg per kilogram of body weight per day . It is also short-term for children and similar to that of adults.

How quickly does Prednisone (Deltasone) work for sinusitis?

Your healthcare provider will tailor the dose and dosage regimen of prednisone to your needs and the severity of an infection. The typical duration after which the symptoms will improve is 4-5 days of medication. You will start to notice the improvement in inflammation, congestion, and pressure after 2-3 days of taking prednisone. 

Complete relief will be observed after 6-7 days of taking Prednisone (Deltasone). Consult your doctor if your symptoms persist for a longer time.

Sinus inflammation can escalate if not addressed promptly. Don’t let it get worse, and talk to your doctor now!

What are the side effects of Prednisone (Deltasone)? 

Some of the common side effects of Prednisone include 

  • Weight gain
  • Increased appetite
  • Insomnia
  • Mood changes
  • Elevated blood sugar levels
  • Fluid retention
  • Increased risk of infection
  • Thinning of skin
  • Easy bruising
  • Muscle weakness

There are also some rare and intense side effects of prednisone as well. Examples include 

  • Severe allergic reactions
  • Vision changes
  • Eye pain
  • Severe mood swings or psychosis
  • Severe stomach or abdominal pain
  • Irregular heartbeat or chest pain
  • Severe headaches
  • Persistent fever
  • Unusual tiredness or weakness
  • Severe joint pain
  • Signs of serious infection, such as high fever or persistent sore throat

These side effects are rare. If observed, it needs immediate medical attention by a healthcare provider. 

Does Prednisone reduce mucus?

Yes, prednisone can help reduce inflammation in the airways and eventually reduce excessive mucus production due to respiratory conditions or sinusitis. 

However, it also depends on the severity of the medical condition, which varies from person to person. Prednisone is often prescribed to manage conditions like asthma or chronic obstructive pulmonary disease (COPD), where reducing airway inflammation can indirectly decrease excessive mucus production.

Persistent sinus pain and inflammation can lead to serious complications. Act now and consult a doctor immediately!

Consult a Doctor

Prednisone cannot be dispensed without a prescription. It’s good to get a consultation and personalized medicine for your sinus infection for the required time. You can now get an online consultation and medication with our healthcare providers. 

FAQs about Prednisone for sinus infection

Will 5mg prednisone help inflammation?

Yes. It can only be if your healthcare provider prescribes it as per the severity of your health condition. The correct dose and dosage regimen can only be decided and prescribed by your healthcare provider if prescribed to you.

Do I need steroids or antibiotics for a sinus infection?

Antibiotics are the first choice of medication for sinus infection, but healthcare providers also prescribe corticosteroids to decrease inflammation and congestion. It also reduces mucus production indirectly.

Does prednisone help with upper respiratory infections?

Yes. Prednisone is prescribed and effective for upper respiratory tract infections, including sinusitis. It also drains the mucus in case of congestion and should only be taken when prescribed by healthcare providers.

What is the treatment for a sinus infection while pregnant?

In pregnancy, it is usually recommended to practice home remedies like steam inhalation, saline nasal sprays, and hydration. Your doctors can also recommend acetaminophen for pain relief. It’s important to note that any medications should only be taken if prescribed or recommended by your doctor!

Your Doctors Online uses high-quality and trustworthy sources to ensure content accuracy and reliability. We rely on peer-reviewed studies, academic research institutions and medical associations to provide up-to-date and evidence-based information to the users.

  • Hayward, Gail, et al. “Intranasal corticosteroids in management of acute sinusitis: a systematic review and meta-analysis.” The Annals of Family Medicine 10.3 (2012): 241-249.
  • Pundir, Vishal, et al. “Role of corticosteroids in functional endoscopic sinus surgery-a systematic review and meta-analysis.” Rhinology 54.1 (2016): 3-19.
  • Snidvongs, Kornkiat, et al. “Sinus surgery and delivery method influence the effectiveness of topical corticosteroids for chronic rhinosinusitis: systematic review and meta-analysis.” American journal of rhinology & allergy 27.3 (2013): 221-233.
  • Mahalingam, Sridhayan, et al. “The role of adjuvant systemic steroids in the management of periorbital cellulitis secondary to sinusitis: a systematic review and meta-analysis.” European Archives of Oto-Rhino-Laryngology 278 (2021): 2193-2201.
  • Gustafson, L. Mark, et al. “Oral prednisone therapy in experimental rhinovirus infections.” Journal of allergy and clinical immunology 97.4 (1996): 1009-1014.

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