Can I take a decongestant while pregnant?

Sick Female Using Nasal Spray to Help Herself
Medically reviewed by Dr. Asim Cheema

Overview

Even a simple cold or allergy flare-up can feel overwhelming when you’re pregnant. You want relief, but the usual go-to medications suddenly come with a big question mark: “Is this safe for my baby?” It’s a common concern, especially when dealing with stuffy noses and sinus pressure that seem to strike at the worst times. Before using any over-the-counter medication, you have to think twice about its effect on your unborn baby. Here is the guide on what is generally safe for the mother and baby alike to get relief from the cold symptoms, what to avoid, and what natural alternatives you can try to feel better. 

What are decongestants?

Decongestants provide short-term relief from a blocked or stuffy nose, commonly caused by colds, flu, allergies, or sinusitis. They reduce the swelling of blood vessels in the nasal passages, helping open up the airways and make breathing easier. Decongestants are available in various forms and can be purchased over the counter at most pharmacies.

When it comes to using a decongestant while pregnant, caution is advised. It’s crucial to ask your healthcare provider what decongestant you can take while pregnant. Decongestants should be used as directed, typically 1 to 4 times daily, but nasal sprays or drops should not be used for more than a week to avoid worsening congestion. If symptoms persist, it’s important to consult your GP. Decongestants are available in several forms, including:

  • Flavored powders to dissolve in hot water
  • Nasal sprays and drops
  • Tablets or capsules
  • Liquids or syrups

All-in-one remedies may contain additional ingredients like painkillers or antihistamines.

While decongestants can be an effective remedy for easing symptoms of sinusitis, cold, and other related conditions, it’s important to use them responsibly, especially during pregnancy and breastfeeding. Always consult a healthcare provider to determine the safest option for you and your baby.

Are decongestants safe during pregnancy?

When considering decongestants during pregnancy, it’s crucial to understand the potential risks and benefits. While some cold medicines are safe for pregnant or breastfeeding women, the safety depends on the ingredients, the stage of pregnancy, and your health conditions. The American Pregnancy Association advises limiting over-the-counter cold medicines during pregnancy and exploring home remedies in mild cases. 

During 1st Trimester

Pseudoephedrine and phenylephrine are common ingredients in decongestants like Sudafed and Sudafed PE. These are classified as pregnancy category C drugs, meaning they should only be used when necessary. There are concerns about using these decongestants during the first trimester due to a potential link to gastroschisis, a rare abdominal wall defect. Although the evidence isn’t consistent across all studies, it’s often recommended to avoid these medications during early pregnancy. 

During 2nd and 3rd Trimester

However, in healthy patients, Sudafed may be considered safe in the second and third trimesters when taken in minimal effective doses.

Using nasal decongestants during pregnancy

For those who prefer nasal decongestants, options like oxymetazoline (found in Afrin) or phenylephrine nasal sprays are also classified as pregnancy category C. These sprays are generally safer due to minimal systemic absorption but should still be used cautiously. The American Pharmacists Association recommends oxymetazoline as the preferred nasal decongestant during pregnancy, as long as it’s used in appropriate doses and for no longer than three days to prevent rebound congestion. 

The safety of decongestants during pregnancy varies depending on the trimester and the specific medication. Always consult your healthcare provider to determine what is safest for you and your baby.

What’s safe in the first trimester can cause birth defects later. Only use provider-approved decongestants during pregnancy.

Which decongestants are safe during pregnancy?

Various cough and cold medications are available over the counter (OTC) at your local pharmacy. These medications target different cold symptoms, so it’s important to pinpoint your specific symptoms before deciding which one to take. However, when you’re pregnant, the choice isn’t as simple. Research on cough and cold medications during pregnancy is limited, and some studies suggest avoiding certain medications, especially during the first trimester, which is a crucial period for your baby’s development.

Weighing risks vs. benefits

Before taking any medication during pregnancy, it’s essential to weigh the risks versus the benefits. Your healthcare provider and pharmacist can help you make the safest choice. They might recommend non-medication options, like a saline rinse, first. If medication is necessary, it’s best to take the lowest dose needed for the shortest duration possible.

Safe cold medications during pregnancy

There are different safe options to take during pregnancy for cough, cold, and runny or stuffy nose, as follows: 

Cough medications

  • Dextromethorphan (Delsym, Robitussin): It is a cough suppressant which is considered safe during pregnancy. However, one study noted a possible link between dextromethorphan and a small number of birth defects. The study’s authors also mentioned that the mothers often used products containing other medications besides dextromethorphan, making it unclear if dextromethorphan was the actual cause. Despite this, dextromethorphan is still generally regarded as safe during pregnancy.
  • Guaifenesin (Mucinex): Used to thin out and loosen chest congestion, guaifenesin is considered safe in the second and third trimesters and likely safe while breastfeeding. It should be avoided during the first trimester. Research on guaifenesin use during pregnancy is limited, so it’s crucial to discuss it with your healthcare provider, especially if you need it during the later stages of pregnancy.

Pain relief for headaches or sore throat

  • Acetaminophen (Tylenol): Acetaminophen is often considered a first-choice pain reliever during pregnancy. Although some research raises questions about its safety, the American College of Obstetricians and Gynecologists (ACOG) recommends it as one of the only safe options. However, it’s best to use acetaminophen only when truly needed and with your healthcare provider’s approval.

Allergy medications during pregnancy

  • Oxymetazoline (Claritin): Often used in allergy medications, oxymetazoline is generally considered safe during pregnancy.
  • Chlorpheniramine (Chlor-Trimeton): Recommended as the antihistamine of choice to treat a runny nose and sneezing during all trimesters of pregnancy.
  • Doxylamine (Unisom) and Diphenhydramine (Benadryl): Also considered safe in all trimesters, though they can cause drowsiness.
  • Cetirizine (Zyrtec) and Loratadine (Claritin): These are safe alternatives for pregnant women and cause less drowsiness. Loratadine is preferred for use while breastfeeding.

Pain relievers and fever reducers

  • NSAIDs (Ibuprofen, Naproxen): While less preferred during pregnancy, NSAIDs can still be used in the first and second trimesters but should be avoided in the third trimester. Pregnant and breastfeeding women should avoid aspirin-containing products.

Natural alternatives to decongestants

If you prefer to avoid medications during pregnancy, several natural alternatives can help alleviate congestion, including:

  • Humidifier: Adds moisture to the air, easing nasal congestion.
  • Hydration: Drinking plenty of fluids helps thin mucus.
  • Warm compress: Apply to your sinuses to relieve congestion.
  • Elevate your head: Sleeping with your head elevated can reduce nasal stuffiness.
  • Hot shower: Steam from a shower can open up nasal passages.
  • Neti pot or saline spray: Helps clear out mucus from nasal passages.
  • Steam inhalation: Inhale steam, optionally with eucalyptus essential oil, to soothe symptoms.
  • Spicy foods: Can temporarily clear sinuses.
  • Saline flush: Use a saline solution to rinse your nasal passages.
  • Apple cider vinegar: Add to a warm drink to help reduce congestion.
  • Herbal teas: Peppermint and other herbal teas can offer relief.
  • Acupressure: Applying pressure to specific points may alleviate congestion.
Pseudoephedrine can cause birth defects during 1st trimester. Avoid the risk and ask the doctor for the safe option.

Decongestants to avoid during pregnancy

When you’re pregnant, it’s crucial to be cautious about the medications you take, including those for common ailments like colds and allergies. Some decongestants that are typically safe for the general population can pose risks to your developing baby. While it’s always best to consult your healthcare provider before taking any medication, this guide will help you understand which decongestants to avoid and why certain alternatives might be safer:

Nasal steroid sprays to avoid

  • Triamcinolone (Nasacort): This nasal steroid spray should be avoided during pregnancy. Research suggests a potential link between triamcinolone and birth defects in the respiratory tract of the fetus. If you need a nasal steroid, consult your doctor for safer alternatives.

Oral decongestants to avoid

  • Pseudoephedrine (Sudafed): The safety of oral decongestants like pseudoephedrine during pregnancy is not well-established. Some studies suggest a higher risk of birth defects, particularly in the first trimester, while others do not. Due to these uncertainties, it’s recommended to avoid pseudoephedrine during the first trimester. If you need a decongestant later in your pregnancy, consult your healthcare provider for safer options.

Nasal decongestant sprays to avoid

  • Oxymetazoline (Afrin): Nasal decongestant sprays like oxymetazoline target nasal congestion directly. However, limited research suggests a possible link between these sprays and birth defects. If your congestion is severe, your provider might recommend using it for a short period (no more than three days) to avoid rebound congestion.

Nonsteroidal anti-Inflammatory drugs (NSAIDs) to avoid

  • Ibuprofen (Advil, Motrin) and Naproxen (Aleve, Naprosyn): NSAIDs are common pain relievers but should be avoided after 20 weeks of pregnancy. At this stage, NSAIDs can reduce amniotic fluid, potentially affecting your baby’s development. At 30 weeks or later, they may cause heart problems in your baby. While NSAIDs might be safer in early pregnancy, they are not the first choice—acetaminophen is generally preferred.

Liquid medications containing alcohol to avoid

  • Alcohol-containing syrups: Some liquid cough and cold medications contain alcohol, which can lead to pregnancy complications, including birth defects. Always check labels to ensure the product is alcohol-free, and consult your doctor if you’re unsure.

Liquid medications containing natural sugars

  • Natural sugars in liquid medications: If you have gestational diabetes, avoid liquid medications with natural sugars, as they can spike your blood sugar levels. Opt for “sugar-free” alternatives, which usually contain safer sugar alcohols like sorbitol or artificial sweeteners like sucralose. However, large amounts of artificial sweeteners can also pose risks, so use them sparingly.

Combination medications to avoid

  • Products Like DayQuil and Claritin-D: Combination cold products often contain multiple active ingredients, some of which may be unsafe during pregnancy. For instance, DayQuil contains a mix of acetaminophen, dextromethorphan, phenylephrine, and guaifenesin, while Claritin-D contains loratadine and pseudoephedrine. It’s best to avoid products containing phenylephrine and pseudoephedrine. Always consult your healthcare provider before using any combination medications during pregnancy.

Why are certain decongestants risky during pregnancy?

While effective at relieving congestion, decongestants can have serious side effects, particularly during pregnancy. These include:

  • Dizziness, anxiety, and nausea: Common side effects of decongestants.
  • Increased blood pressure: Particularly concerning if you have pre-existing conditions like glaucoma, heart disease, or urinary issues.
  • Interactions with other medications: Decongestants can interfere with the effectiveness of medications for blood pressure, epilepsy, diabetes, or thyroid conditions.
  • Potential birth defects: Some decongestants have been linked to birth defects, particularly when used in the first trimester.

Long-term use and combining medications

  • Long-term use: Medications like Sudafed and Nyquil, which contain pseudoephedrine or phenylephrine, should not be used long-term due to the risk of serious side effects, including irregular heartbeat and blood pressure changes. Nasal decongestant sprays like Afrin should be used for no more than three to five days to avoid rebound congestion.
  • Combining medications: Combining decongestants with other medications, herbs, or foods can lead to harmful interactions.

During pregnancy, it’s crucial to be cautious with decongestants and other medications. Always consult your healthcare provider to ensure any treatment you choose is safe for both you and your baby.

Your OTC cold medicine may affect your baby. Get doctor’s advice for safe decongestants during pregnancy

Can you use nasal sprays while pregnant?

During pregnancy, managing nasal congestion can be challenging, especially when you’re trying to navigate which treatments are safe for both you and your baby. When it comes to managing a runny nose or allergies during pregnancy, several options are available:

  • Older antihistamines (First-generation): Medications like chlorpheniramine can help with a runny nose from a cold due to their drying effect. Although these are typically safe during pregnancy, they may cause side effects like sleepiness, dizziness, and dry mouth, which can interfere with daily activities. The American College of Obstetricians and Gynecologists (ACOG) recommends chlorpheniramine as a first-choice option when an antihistamine is necessary.
  • Newer antihistamines (Second-generation): Medications like cetirizine (Zyrtec) and loratadine (Claritin) are less likely to cause drowsiness or other bothersome side effects. However, they may be less effective for cold symptoms and are best avoided during the first trimester unless approved by your healthcare provider.
  • Nasal steroid sprays: Steroid nasal sprays, including fluticasone propionate (Flonase), budesonide (Rhinocort Allergy), and mometasone (Nasonex), are generally considered safe during pregnancy, particularly for treating allergies. These sprays can help with swelling and runny nose caused by a cold. However, they may cause side effects like nosebleeds, dryness, or a burning sensation.

It’s reassuring to know that effective treatments are available for managing allergy and cold symptoms during pregnancy. However, it’s crucial to consult with your healthcare provider before using any over-the-counter medications. Some drugs can cross the placenta and may have unintended effects on your developing baby, so professional guidance is essential for ensuring the safety of both you and your child.

When to consult a doctor?

The American Pregnancy Association recommends contacting your physician if you have a fever of 102°F or higher, cough up thick, yellow-green mucus, experience a cough with chest pain and/or wheezing, or if your symptoms persist without improvement. These signs could indicate a more severe infection that requires medical attention.

Conclusion

Navigating the safety of cold and flu medications during pregnancy can be challenging, but it’s essential for the well-being of both you and your baby. While certain medications, such as dextromethorphan (Delsym, Robitussin) for coughs, chlorpheniramine for a runny nose, and acetaminophen (Tylenol) for pain relief, are generally considered safe, others may pose risks. The key to safely managing cold and flu symptoms during pregnancy is to use medications cautiously. Always consult your healthcare provider before taking any medication, even those available over the counter. When medication is necessary, use the lowest effective dose for the shortest possible duration to minimize potential risks.

Remember, your healthcare provider is your best resource for personalized advice and safe treatment options during pregnancy. By staying informed and seeking medical guidance, you can ensure your and your baby’s health and safety.

FAQs about decongestants during pregnancy

What helps a cough while pregnant?

Most cough drops are generally safe for use during pregnancy, but it’s best to avoid those with menthol in high quantities. Cough suppressants can be used at night to help you sleep, and certain cough syrups, particularly those containing dextromethorphan or guaifenesin, may be recommended by your healthcare provider. 

What happens if you take a decongestant while pregnant?

Generally, physicians consider over-the-counter decongestants safe for use during pregnancy, especially when used for short periods. These medications are designed to relieve sinus congestion and do not typically contain enough active ingredients to cause harm to the baby. However, using them as directed and avoiding prolonged use is important, as overuse could lead to complications. 

What decongestant can I take while pregnant during the first trimester?

During the first trimester of pregnancy, pregnant and breastfeeding women often prefer nasal decongestant sprays such as oxymetazoline (Afrin) and phenylephrine (Neo-Synephrine) to temporarily relieve sinus congestion. These sprays target nasal congestion directly, reducing the risk of systemic side effects that can occur with oral decongestants. However, using these sprays for no more than three days is crucial, as prolonged use can worsen nasal congestion. Always consult with your healthcare provider before using any medication during pregnancy, especially in the first trimester, to ensure it is safe for both you and your baby.

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