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Get a Prescription for Fluticasone Propionate Salmeterol Inhaler Online

Fluticasone/salmeterol inhaler is frequently recommended to treat asthma and chronic obstructive pulmonary disease (COPD). It’s easy to get a Fluticasone/salmeterol inhaler prescription online with Your Doctors Online, where you can consult a doctor whenever and wherever you choose. Please be aware that the Fluticasone/salmeterol inhaler will only be prescribed following a consultation with the physician to ensure that the course of therapy is appropriate and secure for you.

What is fluticasone propionate Salmeterol?

Fluticasone/salmeterol inhaler combines fluticasone propionate, a synthetic anti-inflammatory corticosteroid, with salmeterol, a long-acting beta2-adrenergic agonist. It binds to glucocorticoid receptors in the cytoplasm, regulating gene expression by translocating these receptors to the cell nucleus, thus inhibiting the synthesis and release of inflammatory mediators such as histamines, cytokines, and leukotrienes. Salmeterol stimulates beta2 receptors in the bronchial smooth muscle, leading to prolonged bronchodilation and improved airflow. 

Uses of fluticasone propionate Salmeterol

A fluticasone propionate salmeterol inhaler is a combination medication for managing asthma and chronic obstructive pulmonary disease (COPD). Fluticasone propionate, a corticosteroid, reduces inflammation in the airways, while salmeterol, a long-acting beta2-agonist, relaxes the muscles around the airways to improve breathing. This combination improves overall lung function and quality of life for those with chronic respiratory disorders by preventing and controlling symptoms like wheezing, shortness of breath, and coughing.

How long does it take to work?

The fluticasone propionate salmeterol inhaler begins to work within a few hours after the first dose. Still, its full benefits may take up to 1 week or longer to be noticeable. Salmeterol provides bronchodilation relatively quickly, while fluticasone propionate’s anti-inflammatory effects develop gradually. Consistent, regular use is essential for optimal control of asthma or COPD symptoms, as the medication is designed for long-term management rather than immediate relief of acute symptoms.

What are the dosage forms and strengths of Fluticasone propionate/Salmeterol inhalers?

Fluticasone propionate inhalers come in various dosage forms and strengths to accommodate different treatment needs:

Dosage Forms

  • Available in Common combinations such as:
    • 100 mcg fluticasone/50 mcg salmeterol
    • 250 mcg fluticasone/50 mcg salmeterol
    • 500 mcg fluticasone/50 mcg salmeterol per inhalation.

Various dosage forms and strengths of Fluticasone propionate/Salmeterol inhalers, along with their typical use

  • 100 mcg/50 mcg: Used for maintenance treatment of asthma; suitable for patients needing a lower dose.
  • 250 mcg/50 mcg: Used for maintenance treatment of COPD; moderate dosage for more severe cases.
  • 500 mcg/50 mcg: Used for maintenance treatment of severe asthma; highest dose for maximum anti-inflammatory effect.
  • 55 mcg/14 mcg per inhalation: Used for asthma; lower dose for patients needing minimal medication.
  • 113 mcg/14 mcg per inhalation: Used for asthma; moderate dose balancing efficacy and side effects.
  • 232 mcg/14 mcg per inhalation: Used for asthma; higher dose for more significant symptom control.
  • 45 mcg/21 mcg: Used for asthma; suitable for mild to moderate cases needing lower salmeterol.
  • 115 mcg/21 mcg: Used for asthma; moderate dose for patients needing higher fluticasone with standard salmeterol.
  • 230 mcg/21 mcg: Used for asthma; higher fluticasone dose for severe cases with standard salmeterol.

How to take it?

It is used for long-term control of asthma and COPD.


  • Shake the inhaler well before each use.
  • After taking a deep breath, insert the mouthpiece into your mouth and seal your lips around it.
  • Press the inhaler and breathe in deeply and slowly.
  • After holding your breath for ten or so seconds, gently release it.
  • Rinse your mouth with water without swallowing after each use.
  • Follow your healthcare provider’s instructions, typically one inhalation twice daily.

What are the side effects of fluticasone propionate salmeterol inhaler?

Like all medications, fluticasone can cause side effects. These can range from common and generally mild to rare and potentially serious. The adverse effects can change depending on the fluticasone taken (nasal spray, inhaler, cream, etc.).

Common Side Effects

Rare Side Effects

  • Severe allergic reactions
  • Cardiovascular effects (e.g., increased heart rate, palpitations)
  • Adrenal suppression
  • Growth retardation in children
  • Bone density loss
  • Glaucoma or cataracts

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  • Fluticasone/salmeterol inhaler, 200/ 50 mcg per inhalation.
  • 1 inhalation twice daily. The maximum dose is fluticasone propionate 1,000 mcg/day and salmeterol 100 mcg/day.

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Precautions and contraindications

When using a fluticasone salmeterol inhaler, certain precautions and contraindications should be observed to ensure safe and effective use:


  • Schedule routine check-ups with your family doctor to monitor lung function and adjust the dose if necessary.
  • Rinse your mouth with water after each use to reduce the risk of oral fungal infections (thrush).
  • Inform your doctor of any history of heart disease, high blood pressure, seizures, diabetes, thyroid disorders, infections, or osteoporosis.
  • The medication can weaken your immune system, making you more susceptible to infections.
  • Inform your family doctor of all medications you are taking to avoid potential drug interactions.
  • If you are pregnant or nursing, discuss the advantages and disadvantages. To your doctor.
  • Use the lowest effective dose of corticosteroids for the shortest time required to reduce systemic adverse effects.
  • Special caution is needed in children and the elderly, as they may be more sensitive to the medication’s effects.


  • Do not use it if allergic to fluticasone, salmeterol, or other inhaler components.
  • Do not use the inhaler to treat sudden breathing problems or acute asthma attacks; a rescue inhaler is required.
  • Avoid use if you have an active untreated infection, as the medication can suppress the immune response.
  • They are contraindicated in patients with severe hypersensitivity to milk proteins (some formulations contain lactose).
  • It is not recommended for individuals with severe cardiovascular disorders, severe liver impairment, or active tuberculosis without medical supervision.
  • Avoid use if you have untreated systemic fungal, bacterial, viral, or parasitic infections.

FAQs about Fluticasone Salmeterol Inhaler

Is fluticasone salmeterol the same as Advair?

Yes, fluticasone salmeterol is the same as Advair. Advair is the brand name for the combination of fluticasone propionate and salmeterol xinafoate used to manage asthma and COPD. For children, the dosage may be according to age and weight.

What is the most common adverse effect of using a salmeterol fluticasone inhaler?

The most frequent side effect is a fungal infection of the mouth and throat called oral thrush. To help avoid this, mouthwash should be rinsed out after each use.

Does fluticasone salmeterol cause weight gain?

Weight gain is not a common side effect of fluticasone salmeterol. However, long-term use of corticosteroids like fluticasone can lead to weight gain.

Does fluticasone salmeterol raise blood pressure?

Fluticasone salmeterol is not commonly associated with raising blood pressure. However, salmeterol may affect heart rate, so monitoring is advisable for those with cardiovascular concerns.

Does salmeterol affect the heart?

Yes, it can cause palpitations, increased heart rate, or, in rare cases, arrhythmias. Therefore, it should be used with caution in patients with heart conditions.

Is it wrong to use fluticasone salmeterol every day?

Using fluticasone salmeterol daily as prescribed is generally safe and essential for managing chronic respiratory conditions. However, it should be used under the guidance of a healthcare provider to avoid potential long-term side effects.

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