How to take Doxycycline for sinus infection?

doxycycline for sinus infection
Medically reviewed by Dr. Mandy Liedeman

Key Takeaways

  • Sinus infection, also called sinusitis, is a bacterial infection that needs medical consultation and a dosage regimen for complete treatment. 
  • Healthcare providers prescribe doxycycline for sinus infections, which helps relieve the symptoms and treats infection. 
  • Doxycycline works by stopping the growth of bacteria and making unfavorable conditions for bacteria to survive in the body, eventually leading to the death of a bacteria. 
  • Consult your healthcare provider for the correct diagnosis and dosage regimen per your medical needs. 

Overview

Doxycycline is an effective antibiotic for treating sinus infections caused by bacteria. It is especially recommended for people allergic to penicillin-type antibiotics, including amoxicillin. However, it is not available over the counter but only upon a doctor’s prescription. The typical starting dose of doxycycline for sinus infection in adults is 100mg twice daily for 7 to 14 days. It is recommended to be taken with water and after meals to avoid GIT disturbances. Consultation with your healthcare provider is beneficial for accurate diagnosis and dosage regimen. 

Need Doxycycline for your sinus infection?

Your Doctors Online can provide accurate diagnosis and prescriptions to treat your infection effectively now.

Connect right away and start your recovery today!

Is doxycycline good for sinus infection?

Yes, Doxycycline is good for sinus infections and is recommended by healthcare providers. It is also prescribed, especially when a person has a penicillin allergy, and can be treated with any penicillin antibiotics. 

It’s not an over-the-counter medication and needs a medical prescription to get dispensed as it can only be determined by your healthcare provider.

How does Doxycycline work for a sinus infection?

Doxycycline has bacteriostatic properties and functions to inhibit the growth of bacterial proteins important for bacterial replication. It targets the growth and reproduction of the bacteria, leading to bacterial cell death. 

How to take Doxycycline for sinus infection?

You can take doxycycline for sinus infection in the form of oral capsules in the following dosage forms:

  • Children 8 years onwards: Children weighing 45 kg or more can start with 100mg of doxycycline every 12 hours. Doctors recommend 100mg daily or 50mg every 12 hours from the next day. However, children who weigh less than 45kg should take the dosage as per their body weight, i.e., 4.4mg/kg. Therefore, discussing with a healthcare professional before taking an antibiotic dose for a sinus infection is best. 
  • Adults: For starters, take 100mg every 12 hours and then reduce it to 50mg every 12 hours or a single dose of 100mg per day. 

Your doctor may also recommend taking doxycycline on an empty stomach or sometimes with food to avoid stomach irritation. Therefore, discuss with your doctor how you should take doxycycline for sinus infection based on your medical history, sensitivities, infection type, and age. Finish the entire course of medication, which usually takes 7-14 days, even if symptoms improve, to ensure the infection is completely treated.

What are the alternative medications for sinus infection? 

There are alternative medications you can take in case doxycycline doesn’t suit you. As per your doctor’s prescription, you can take the following alternative medications for sinus infection: 

Only go for alternative options as per your doctor’s advice and prescription.   

Struggling with sinus infection symptoms but allergic to penicillin?

Your Doctors Online offers Doxycycline as an alternative antibiotic. Get a personalized prescription quickly and start treating your infection.

Consult a doctor now and feel better soon!

What side effects should you expect with Doxycycline?

Here are some of the most common and severe side effects of doxycycline: 

Common side effects:

Severe side effects:

The following are less common but potentially severe side effects that require immediate medical attention: 

  • Severe skin reactions (e.g., blistering, peeling, or a widespread rash)
  • Difficulty swallowing or breathing
  • Swelling of the face, lips, throat, or tongue
  • Severe headache or blurred vision
  • Chest pain or irregular heartbeat
  • Dark urine or yellowing of the eyes or skin (jaundice)
  • Severe stomach or abdominal pain
  • Persistent vomiting or diarrhea
  • Signs of a severe allergic reaction (e.g., hives, itching, or difficulty breathing). 

What are the precautions of taking Doxycycline for a sinus infection?

There are certain precautions you should practice before taking doxycycline for sinus infection:

  • Consult your doctor if your symptoms don’t improve or worsen after a few days instead of abruptly stopping the medication. 
  • If you have stomach sensitivity, tell your doctor beforehand, as it can irritate your stomach further and cause diarrhea. 
  • It can darken the color of your skin, nails, gums, and teeth. If you notice any of these signs, discuss them with your doctor.
  • If you are pregnant, taking doxycycline can be harmful. 
  • If you are on birth control, doxycycline can interfere with its functioning. Either use other forms of contraceptives while using doxycycline or ask your doctor to prescribe an antibiotic that doesn’t interfere with the process of birth control. 
  • Avoid exposing yourself to direct sunlight, as it can make your skin sensitive and cause a rash or discoloration of the exposed area. 
  • Avoid taking over-the-counter medications, including Tylenol or Advil, along with doxycycline, as it can interfere and cause irritation. 

Doxycycline is effective for sinus infections, but it requires a prescription.

Speak to one of our healthcare professionals at Your Doctors Online to get diagnosed and receive a prescription immediately.

Get a Doxycycline prescription now!

Can low-dose doxycycline help or cure chronic sinusitis?

Yes, low-dose doxycycline can help cure chronic sinusitis. A study examined how low-dose oral doxycycline effectively treats chronic rhinosinusitis with nasal polyps that don’t respond well to surgery and steroids. Researchers worked with 60 patients, splitting them into two groups: one group received nasal steroids plus doxycycline, while the other group received only nasal steroids. 

Over 12 weeks, the group taking doxycycline showed significant improvement in symptoms compared to the steroid-only group. However, patients with asthma, aspirin sensitivity, or high IgE levels didn’t see as much benefit. Overall, doxycycline could be helpful for patients with chronic rhinosinusitis and nasal polyps, especially those without these additional conditions.

How long does it take for doxycycline to clear a sinus infection?

Doxycycline starts working within 2 days of the initial dose. However, a 7-14-day course should be completed to nullify the infection completely. Consult your healthcare provider for an appropriate dosage regimen and duration for your condition. 

When should I see a doctor?

Doxycycline is an antibiotic that requires a prescription and a dosage regimen before being dispensed to you. You can get a consultation and prescription for your medical condition from our healthcare providers anywhere around the globe. 

FAQs about Doxycycline for sinus infection

Can I request a Doxycycline prescription from my healthcare provider?

Yes, you can. If you need a Doxycycline prescription, you can request a prescription. Other alternatives can be online prescription request services, where you can get one by requesting in with our mobile app.

Can I use Doxycycline for sinus infections during pregnancy or while breastfeeding?

It is generally not recommended to use Doxycycline while pregnant or breastfeeding due to its penetration properties from the placenta to the developing fetus. It can cause fetal anomalies, including impaired tooth and bone development.

What should I do if my symptoms persist after completing a Doxycycline course?

Consult your healthcare provider before continuing Doxycycline or any other medication to adequately cater to your medical needs. Discuss your medication and medical condition history with your healthcare provider for the correct diagnosis. 

What are the drug Interactions with Doxycycline?

Doxycycline shows interactions with drugs, including antacids having aluminum, calcium, or magnesium, penicillin antibiotics, anticoagulants (warfarin), barbiturates, some seizure medications (phenytoin, carbamazepine), oral contraceptives, Isotretinoin and bismuth subsalicylate

Your Doctors Online uses high-quality and trustworthy sources to ensure content accuracy and reliability. We rely on peer-reviewed studies, academic research institutions and medical associations to provide up-to-date and evidence-based information to the users.

  • Cunha, Burke A., Carol M. Sibley, and Angela M. Ristuccia. “Doxycycline.” Therapeutic drug monitoring 4.2 (1982): 115.
  • Stalman, W., et al. “The end of antibiotic treatment in adults with acute sinusitis-like complaints in general practice? A placebo-controlled double-blind randomized doxycycline trial.” British journal of general practice 47.425 (1997): 794-799.
  • Axelsson, A., and J-E. Brorson. “Concentration of Antibiotics in Sinus Secretions: Doxycycline and Spiramycin.” Annals of Otology, Rhinology & Laryngology 82.1 (1973): 44-48.
  • Axelsson, Alf, et al. “Treatment of Acute Maxillary Sinusitis: Doxycycline and Spiramycin with and without Irrigation.” Annals of Otology, Rhinology & Laryngology 82.2 (1973): 186-191.

Get started today

Talk to online doctors now and get medical advice, online prescriptions, and referrals within minutes. On-demand healthcare services at your fingertips.

talk to online doctor 24/7 free