Consult & collect your Levothyroxine (Synthroid®) refill prescription online

In one quick virtual consultation, our providers will assess your TSH and T4 history, lifestyle factors, and dosing needs, then e-prescribe the appropriate regimen for your refill prescription of Levothyroxine for a same-day pickup.

Levothyroxine
Levothyroxine

Trusted by millions for instant online care

Over 500,000+ Patients

5-star Doctor Ratings

4.8 Rating

20k+ App Reviews

4.6 Rating

1k+ Trustpilot Reviews

Renew your Levothyroxine (Synthroid®) online & pickup in few hours

Never miss a dose or wait weeks for a renewal. A licensed provider will authorize your refill and send it straight to your chosen pharmacy in one quick telehealth visit.

Select your pharmacy

Whether it’s your neighborhood drugstore, a nationwide chain, or a mail-order service, simply tell us where you’d like your Synthroid® refill to be sent. There is no need for in-person paperwork.

Fast, same-day pickup

Your electronic prescription goes live as soon as your doctor signs off. Most pharmacies have your Levothyroxine ready within hours.

Real-time alerts

Our app sends you instant updates when your refill is approved, transmitted, and waiting at the counter, so you know exactly when to pick it up and regain control of your thyroid health.

How do you refill your Levothyroxine (Synthroid®) online?

Keep your thyroid levels steady without an in-person visit; our telehealth service lets you renew your Synthroid® prescription in minutes.

1

Start your virtual appointment

Open the “Your Doctors Online” app or secure portal, log in, and complete a quick health intake. Share your recent lab results (TSH, T4), symptoms like fatigue or weight changes, and other medications to ensure that you are taking the correct dosage.

2

Consult with a specialist

Choose video, audio, or chat. Your provider will review your hormone levels, discuss your symptoms, and confirm or adjust your levothyroxine dose to keep you at the optimum dose.

3

Get your e-prescription

Once approved, we’ll send your Synthroid® refill to the pharmacy you select, local, national chain, or mail order. Most patients pick up their medication the same day, so you never miss a dose.

Who qualifies for an online Levothyroxine (Synthroid®) refill prescription?

You may be eligible to renew your thyroid medication via telehealth if you meet any of the following criteria, and a licensed provider confirms it during your virtual visit:

What are the dosages & strengths of Levothyroxine (Synthroid®)?

When you refill Synthroid®, your provider will select the tablet strength that matches your current regimen. Common strengths include:

Side effects of Levothyroxine (Synthroid®)

Most people tolerate replacement therapy well, but you may notice:

These effects often settle as your body adjusts to the correct dose. If you experience chest pain, rapid or irregular heartbeat, severe headache, or symptoms of overtreatment (e.g., insomnia, excessive sweating), contact your provider immediately for a dose reassessment.

Contraindications & precautions for Levothyroxine (Synthroid®) refills

Before renewing your Synthroid® prescription online, your provider will review for any of the following:

  1. Allergy to Levothyroxine or excipients: Do not refill if you’ve had a hypersensitivity reaction (rash, swelling, difficulty breathing) to this or similar thyroid hormones.
  2. Untreated adrenal insufficiency: Starting or increasing thyroid dose can precipitate an adrenal crisis; confirm adequate steroid replacement first.
  3. Recent myocardial infarction or unstable heart disease: Thyroid hormones increase cardiac workload; use with caution and under close supervision.
  4. Uncontrolled diabetes: Levothyroxine can alter glucose metabolism; monitor blood sugar levels when adjusting your dose.
  5. Osteoporosis or low bone density: Long-term overtreatment can accelerate bone loss. Ensure your TSH remains within the target range.
  6. Age-related dosing considerations: Elderly or frail patients may require lower doses to avoid cardiac or bone-related side effects.
  7. Drug interactions: Certain supplements (iron, calcium) and medications (PPIs, anticonvulsants) can impair Levothyroxine absorption. Therefore, it is recommended that you take Levothyroxine on an empty stomach and separate dosing by at least 4 hours.
  8. Pregnancy & breastfeeding: Thyroid requirements change during pregnancy; confirm trimester-specific dosing with your provider and adjust as instructed.

Note: Always share your complete medical history, including recent lab results, other medications, and any new symptoms, during your telehealth refill visit to ensure safe, effective thyroid hormone management.

Telemedicine consultation for prescription medicine

Get a Levothyroxine refill prescription from online doctors

FAQs: Levothyroxine (Synthroid®) refills online

Levothyroxine (brand name Synthroid®) is the most commonly prescribed thyroid hormone replacement worldwide. Its well-established efficacy and safety profile make it a first-line therapy for hypothyroidism.

Physicians exercise caution because Levothyroxine dosing must be individualized: over-replacement can cause heart palpitations, bone loss, or anxiety, while under-replacement leaves the patients symptomatic. They often require recent lab tests (TSH, T3, free T4) and clinical evaluation before issuing or adjusting a prescription.

Levothyroxine is generally well tolerated when dosed correctly. Because it is identical to endogenous T4, side effects are uncommon if TSH is kept within the target range. Alternatives (e.g., desiccated thyroid extract) carry a higher risk of dose variability and adverse reactions.

With our telehealth service, simply register, complete a brief intake (including your last TSH value), and meet virtually with a provider. If you qualify, they will e-prescribe your Synthroid® and a refill will be faxed directly to your chosen pharmacy.

Unopened Levothyroxine retains full potency until the expiration date printed on the package (typically 18–24 months from manufacture). After opening, most manufacturers recommend using it within one year, stored in its original container away from moisture and heat.

Yes, once you have a valid prescription. After your telehealth consult, your e-script can be sent to any participating online or brick-and-mortar pharmacy for same-day or mail delivery.

No. Levothyroxine is a prescription-only medication because dose monitoring via TSH and periodic lab tests is necessary. Any site claiming to sell it OTC operates outside legal regulations and may supply unsafe products.

We offer transparent plans, such as a family sharing plan. Before your virtual visit, you’ll see all costs upfront before agreeing to refill your prescription.

Levothyroxine replaces deficient thyroid hormone in conditions such as primary hypothyroidism (e.g., Hashimoto’s), post-thyroidectomy, or after radioactive iodine therapy. It normalizes metabolic functions, energy levels, and temperature regulation.

Take your tablet once daily on an empty stomach, ideally 30–60 minutes before breakfast, with a full glass of water. Avoid calcium, iron, or antacids within four hours of your dose, as they impair absorption.

If you forget, take it as soon as you remember, unless it’s within 4 hours of your next scheduled dose. Do not double up. Consistency is key to maintaining steady thyroid levels.

You may feel symptomatic improvement (less fatigue, clearer thinking) within 2 weeks, but complete biochemical stabilization (normal TSH) can take 6–8 weeks. Your provider will schedule follow-up labs accordingly.

No. Even small changes in Levothyroxine (e.g., from 100 mcg to 112 mcg) significantly affect thyroid levels. Always consult your provider via telehealth before making any dose adjustments.

It takes time for the body to adjust to the medicine. Generally, individuals notice an improvement 6 weeks after taking Levothyroxine. For others, it can take longer to see significant effects.

Levothyroxine has several drug interactions. Some classes of drugs that it interacts with include Antacids, Bile acid sequestrants, PPIs, Beta-blockers, etc. It also interacts with beverages and food items, including coffee, grapefruit juice, alcohol, walnuts, etc.

Levothyroxine (Levoxyl, Synthroid, etc.) must be taken lifelong by individuals who have undergone a thyroidectomy or radioiodine therapy. It provides thyroid hormones to the body. Medication is also required to maintain a healthy blood calcium level if the parathyroid glands have been removed during surgery.

We've satisfied millions of patients at YDO

Phindile Mkhatshwa
This is the best app..You ask anything and the doctors answer you within minutes, i love it.
-brooke snow
It is a good app, it can be helpful with pictures and be very detailed.
-Okiti Stephanie
Wow, these people are such a blessing. Dey give accurate answered to questions asked. Its really too good
-ASIF Khan
Impressive work !! Connecting to a doctor was so quick. I am really impressed.
-Chelsey
Doctor was really great, fast at responding very helpful.
-edith bien aime
Chat with them the doctor that I chat with very helpful and answer all my questions I recommend to anyone.
-Lesego Thejane
The best patient doctors that understand and give you useful information ..I'm really thankful.
-Stephanie Brown
Very informative and very detailed in explanations.Also pleasant and courteous.I would recommend to anyone.
-kulwinder gill
Very helpful, very polite and answers every question in a well mannered way.
-Elijah Mark
I really rate this website a lot, you people don't stick and and im sure you try your best to take swift actions for your patients.

Request a same-day Levothyroxine refill prescription today