Skip the urgent care wait. Get a Fosfomycin (generic Monurol) online prescription to start UTI treatment quickly
Burning when you pee. Pelvic pressure that won't ease. The fear that it is spreading to your kidneys while you wait days for a clinic slot. Get Fosfomycin online by connecting with a licensed doctor in minutes. The doctor will evaluate your symptoms and issue a prescription if it is medically appropriate.
- Single 3g sachet — one dose, no 5 to 7-day antibiotic course
- Symptom relief usually starts in 24 to 48 hours
- Prescription sent to a pharmacy near you, often within the hour
Why Choose Your Doctors Online to get a Fosfomycin prescription
You don't have to take time off work, sit in a clinic waiting room, or pay an urgent care copay to treat a routine bladder infection. Your Doctors Online is built differently from a walk-in or an ER.
Same-day Fosfomycin prescription, no waiting room
You can chat with a doctor within minutes of opening the app. If Fosfomycin is the right fit for your UTI symptoms, the prescription is sent to your pharmacy the same day you book.
US-licensed doctors trained on the IDSA UTI guideline
Every prescription is reviewed by a physician licensed in your state who follows the IDSA acute uncomplicated cystitis guideline. That means Fosfomycin gets chosen for the right patient, not as a default fast-track.
Unlimited follow-up chats included
If your UTI symptoms don't improve within 24 to 48 hours after the single dose, you can message the same doctor again without paying. Most plans charge per visit. Your Doctors Online includes follow-up in the flat monthly fee.
HIPAA-compliant care across all 50 states
Your chat, video, and medical history stay encrypted and HIPAA-compliant. Online prescription requests are routed to a doctor licensed in the state you're in, every time.
How to get a Fosfomycin prescription online
You can request a Fosfomycin prescription online through Your Doctors Online without a clinic visit. The complete process takes about 15 minutes, so you can start your treatment immediately. To buy Fosfomycin online from a US pharmacy, you need that prescription first; there is no over-the-counter option.
Tell the doctor about your symptoms
Open a chat with a doctor and describe what's happening. Burning during urination, frequent urgency, lower belly pressure, cloudy or strong-smelling urine. The doctor will ask when symptoms started, whether you have a fever or back pain, and whether you've had a UTI in the last few months. These details rule out a kidney infection, which Fosfomycin does not treat.
Get evaluated and screened for eligibility
The doctor screens for an uncomplicated UTI. If your symptoms point to anything outside that, you will be referred for an in-person evaluation or a urine culture. This is the screening that protects you from being given the wrong antibiotic for a kidney infection or a sexually transmitted infection that mimics UTI symptoms.
Pick up your prescription
If Fosfomycin is the right fit, your prescription is sent electronically to a pharmacy near you. Most patients pick it up the same day. Take the single 3g sachet that night, on an empty stomach, and dissolve it in 3 to 4 ounces of cold water.
What is Fosfomycin (and is it the same as Monurol)?
Fosfomycin is a single-dose antibiotic for urinary tract infections. It was sold in the US under the brand name Monurol for years, but the brand was discontinued. In November 2024, the FDA approved a generic version of Fosfomycin tromethamine 3g granules. When a pharmacy fills your prescription, you receive the FDA-approved generic. The medicine, the dose, and the way it works are identical to the original Monurol.
Fosfomycin works by stopping bacteria from building their cell walls. Because that mechanism is different from how penicillins, cephalosporins, or fluoroquinolones (like Cipro) kill bacteria, there is very little cross-resistance. A bacterial strain that has stopped responding to TMP-SMX or Cipro may still respond to Fosfomycin, which is why it stays useful as resistance to other UTI antibiotics rises.
What is Fosfomycin used for?
Fosfomycin for UTI is FDA-approved only for uncomplicated urinary tract infection (acute cystitis) in adult women, caused by susceptible strains of Escherichia coli or Enterococcus faecalis.
Fosfomycin
Generic • Monurol (brand, discontinued)Who is eligible for a Fosfomycin prescription online?
Fosfomycin is effective for a specific type of UTI in a specific group of people.
You are likely a fit if
All of the following apply
Contraindications and precautions
Check with a doctor first
How much does Fosfomycin cost?
Fosfomycin price in the US depends on the pharmacy and whether you use insurance, a Medicare Part D plan, or a discount card. Generic Fosfomycin tromethamine is the version dispensed in US pharmacies, since the brand Monurol was discontinued.
| Cost scenario | Generic Fosfomycin tromethamine 3g sachet | Brand Monurol 3g sachet |
|---|---|---|
| YDO consult fee | $20 / month (flat) covers consult + prescription + lab orders + doctor's note (no per-Rx charge) | Same flat fee. The drug name doesn't change the consultation cost. |
| Pharmacy wholesale (CMS NADAC, Feb 2026) | $33.88 to $35.89 per sachet (varies by manufacturer: Xiromed LLC at $33.88, Cipla USA at $35.89) | Brand discontinued in the US since 2024 |
| Pharmacy fill, with Medicare Part D | Typically placed on Tier 1 or Tier 2 of most Medicare Part D formularies. Copay varies by plan. | Not applicable (brand discontinued) |
| Pharmacy fill, no insurance | Retail price varies by pharmacy. The pharmacist can quote the cash price before you fill. Generic placement is widespread after FDA approval of Aurobindo's ANDA 217608 in Nov 2024. | Not applicable |
Fosfomycin dosage: How much, how to take it, how many days
Fosfomycin for UTI is the only oral antibiotic approved by the FDA as a single-dose treatment for adult women with uncomplicated UTIs.
| Dose | Form | Frequency | Maximum course |
|---|---|---|---|
| 3 g | Granules for oral solution (sachet, dissolved in 3 to 4 oz cold water) | One time | 3 g per UTI episode |
Fosfomycin dosing is straightforward: pour the 3g sachet into half a glass of cold water, stir, and drink immediately. Fosfomycin tromethamine can be taken with or without food and is readily absorbed.
Side effects of Fosfomycin (Monurol)
Because Fosfomycin is given as a single dose, side effects tend to be short-lived. The most common ones reported in FDA-approved clinical trials are:
Common side effects
Uncommon or rare side effects
Meet our doctors prescribing Fosfomycin
Dr. Richard Honaker is a board-certified physician with more than 40 years of experience in family and emergency medicine. He serves as Chief Medical Advisor at Your Doctors Online and is affiliated with Medical City Plano in Texas. Recognized multiple times by D Magazine and Texas Monthly, Dr. Honaker provides evidence-based care across a wide range of conditions including diabetes, hypertension, and injury care.
Dr. Monique Rainford is an OB/GYN expert and Assistant Clinical Professor at Yale School of Medicine. With 25+ years of experience, she’s led OB/GYN departments at Yale Health and Baltimore Medical System. Her clinical interests include pregnancy, menstrual health, chronic pelvic conditions, and lifestyle medicine. Dr. Rainford advocates for maternal health equity, especially in underserved communities.
Dr. Candice Fraser is an OB/GYN practitioner and founder of Trinity Medical Care. With over a decade of experience, she focuses on reproductive care, menstrual health, and menopause management. Along with medical training and residency, she also holds an MBA in healthcare management, blending business insight with clinical excellence.
Frequently asked questions
How fast does Fosfomycin work?
Most women start feeling better within 24 to 48 hours after taking Fosfomycin. The medicine quickly accumulates in the urine and continues to work against bacteria in the bladder for the next couple of days, with full bacterial clearance usually occurring by days 2 to 3. If your symptoms are not improving by day 3, contact your doctor. It may mean the bacteria is resistant, the infection has spread beyond the bladder, or something other than a UTI is causing your symptoms. A urine culture and a different antibiotic may be needed.
Can I buy Fosfomycin (Monurol) over the counter in the US?
No, Fosfomycin is not available over the counter. It is a prescription-only antibiotic in the United States. You cannot walk into a CVS, Walgreens, or Rite Aid and buy a sachet off the shelf. The FDA classifies it as a prescription medicine because UTI symptoms can mimic other infections (kidney infections, sexually transmitted infections, interstitial cystitis), and self-treating with the wrong antibiotic delays the right care.
Online prescribing is the closest you can get to OTC. A licensed doctor reviews your symptoms over chat, writes the prescription if Fosfomycin is the right fit, and sends it to your pharmacy.
Is the brand Monurol discontinued?
Yes. The brand-name Monurol was discontinued in the US. The FDA approved a generic version of Fosfomycin tromethamine 3g granules in November 2024. The active ingredient, strength, dose, and mechanism of action are identical to those of the original Monurol. The bottle just says “Fosfomycin tromethamine” instead of “Monurol”.
How long does it take Fosfomycin to cure a UTI?
Symptom relief usually starts within 24 to 48 hours of the single dose. Full clearance of the bacteria takes about 2 to 3 days. If your symptoms aren’t improving by day 3, call the prescribing doctor. That can mean the bacteria are resistant to Fosfomycin, the diagnosis was wrong, or the infection has moved beyond the bladder.
What should I avoid while taking Fosfomycin?
Three things matter for Fosfomycin interactions. First, do not take metoclopramide (Reglan) at the same time. Metoclopramide speeds up gastric motility and reduces the amount of Fosfomycin absorbed, lowering urinary concentration and weakening the Fosfomycin UTI dose.
Can I take Fosfomycin if I'm pregnant?
Sometimes. The FDA pregnancy category system has been retired, but ACOG’s 2023 guidance on urinary tract infections in pregnancy lists Fosfomycin as a reasonable single-dose option for acute cystitis and for asymptomatic bacteriuria, depending on culture results. Fosfomycin crosses the placenta, but no consistent harm has been reported in pregnancy studies. The decision to prescribe in pregnancy is one your obstetric provider should sign off on, since urine culture and follow-up are usually expected. An online doctor without obstetric records will most often defer to your OB.
Can men take Fosfomycin for a UTI?
Not under the FDA approval. Fosfomycin is FDA-approved only for women with uncomplicated UTIs. Some research and infectious-disease specialists use it off-label in men for complicated UTIs, prostatitis caused by multi-drug-resistant bacteria, and prostate-biopsy prophylaxis, usually as multi-dose courses.
Is Fosfomycin a strong antibiotic?
Yes, but not the strongest option for every UTI. In the largest head-to-head study, one 3g dose of Fosfomycin cleared the infection in 58% of women at 28 days. A 5-day nitrofurantoin course cleared 70% in the same study. IDSA still lists Fosfomycin as a first-line UTI antibiotic because it works against bacteria that have stopped responding to Bactrim, Cipro, or nitrofurantoin, and one dose is easier to finish than a 5-day course. It’s the right choice for a bladder infection, not for a kidney infection.
Is Fosfomycin better than Cipro for UTI?
For an uncomplicated lower UTI in a non-pregnant adult woman, Fosfomycin is the better choice. The IDSA places it in the first-line tier and Cipro in the second-line tier. Cipro resistance in US community E. coli often exceeds 30%, while Fosfomycin resistance remains around 5-7%. The FDA has issued repeated warnings about fluoroquinolones (including Cipro) for low-risk infections due to risks of tendon rupture, peripheral neuropathy, and aortic aneurysm. For a more serious or complicated UTI, the decision is up to the prescribing doctor, based on culture and history.
Which works better for UTI: Fosfomycin or Macrobid?
Both are first-line antibiotics for uncomplicated UTIs. Macrobid (Nitrofurantoin) for UTI has the lowest resistance rates and is commonly used for 5 days, while Fosfomycin is taken as a single dose, making it more convenient for some women.
