Does Ibuprofen Raise Blood Pressure?

does Ibuprofen raise blood pressure
Medically reviewed by Dr. Mavra Farrukh

Key Takeaways

  1. Ibuprofen may have a slight, consistent impact on raising blood pressure over an extended period.
  2. Individuals with heart or blood pressure conditions should consult their medical professional before considering ibuprofen.
  3. Various medications and natural alternatives are available for treating mild to moderate pain and fevers, offering options with potentially fewer side effects.


If you’re suffering from high blood pressure, it’s crucial to be mindful of the effects that common over-the-counter (OTC) medications can have on your condition. Some widely used drugs, such as Advil and Aleve, along with certain antacids, can raise blood pressure. Whether you’re controlling hypertension through diet or prescribed medications, it’s important to consult your healthcare provider before using any OTC drugs or supplements. This blog will specifically explain the impact of Ibuprofen (Advil, Motrin), a non-steroidal anti-inflammatory drug (NSAID), on blood pressure. Known for its effectiveness in treating mild to moderate pain, fever, menstrual cramps, rheumatoid arthritis (RA), and osteoarthritis (OA), Ibuprofen is readily available in the pharmacy’s OTC section. It can also be obtained in higher doses with a prescription. For those with high blood pressure, there’s often a concern about the potential of Ibuprofen to raise blood pressure. 

If you are facing hypertension consult a doctor now!

What does ibuprofen do to the body? 

Ibuprofen, categorized as a non-steroidal anti-inflammatory drug (NSAID), operates by alleviating pain and inflammation by inhibiting substances in the body known as prostaglandins. Prostaglandins play diverse roles within our bodies. While commonly associated with generating pain, fever, and inflammation during illness or injury, they also influence critical functions such as the dilation and constriction of blood vessels, protecting the stomach lining, and regulating blood clotting.

Ibuprofen’s effectiveness lies in its ability to block the effects of prostaglandins. Doing so successfully mitigates pain, reduces fever, and addresses inflammation. However, it’s important to note that because prostaglandins serve multiple functions, inhibiting their effects through ibuprofen can lead to various side effects, including increased blood pressure.

What are the risks of taking Ibuprofen with high blood pressure?

Daily consumption of ibuprofen, whether in the form of Advil or Motrin, poses risks beyond its potential impact on blood pressure. Before incorporating ibuprofen into your daily routine, you must be aware of these risks and discuss them with your healthcare provider.

Gastrointestinal Discomfort and Bleeding

Ibuprofen’s influence on prostaglandins elevates the risk of stomach ulcers and bleeding. This risk increases, especially if you also take anticoagulants (blood thinners). Taking ibuprofen with food may alleviate stomach discomfort, but consult your healthcare provider for suitable prescription medications if issues persist. For those advised to take ibuprofen regularly, discussing long-term options to protect the stomach and digestive tract is crucial.

Higher Risk of Serious Bleeding

While not classified as a blood thinner, ibuprofen carries a low but existing risk of serious bleeding. Individuals with liver cirrhosis should avoid ibuprofen due to an increased bleeding risk. Additionally, ibuprofen interferes with platelets’ ability to control bleeding. If you have a history of thrombocytopenia (low platelet count), ibuprofen may heighten the risk of bleeding.

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Heart Attacks and Heart Failure

Studies indicate that ibuprofen, particularly at doses exceeding 2,400 mg per day, raises the risk of heart attacks. NSAIDs, including ibuprofen, have also been associated with a higher likelihood of hospitalizations in individuals with heart failure. If you have a history of heart problems, consulting your healthcare provider before using ibuprofen or other NSAIDs is advisable.

Asthma Attacks

Individuals with asthma, nasal polyps, or sinus inflammation should consult their healthcare provider before taking NSAIDs, including ibuprofen. Such conditions elevate the risk of uncontrolled asthma symptoms when using aspirin or other NSAIDs.

Kidney Damage

By narrowing the blood vessels in the kidneys by inhibiting prostaglandins, ibuprofen can lead to kidney damage over time. Those with chronic kidney disease (CKD) face a higher risk, but this kidney damage is typically reversible upon discontinuing ibuprofen.

Understanding these potential risks is vital for making informed decisions about ibuprofen use, particularly for individuals managing high blood pressure. 

Is it safe to take Ibuprofen if I have high blood pressure?

Numerous studies indicate that ibuprofen has the potential to elevate blood pressure, particularly in individuals with hypertension. This effect may also extend to those already taking blood pressure medications. While the observed changes in blood pressure tend to be small in these studies, they are indeed noticeable.

Given these findings, some experts caution individuals with hypertension against using non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. Moreover, individuals with heart failure and chronic kidney disease (CKD), including CKD linked to diabetes, face an increased risk of experiencing blood pressure changes after NSAID consumption.

If you are facing hypertension consult a doctor now!

How much does ibuprofen raise your blood pressure?

Researchers have conducted studies to assess how much non-steroidal anti-inflammatory drugs (NSAIDs), particularly ibuprofen, influence systolic blood pressure (SBP), the upper number in blood pressure measurements. 

Studies suggest that, on average, a person’s SBP may rise by approximately five mmHg after taking NSAIDs like ibuprofen. A review specifically focusing on the impact of ibuprofen on blood pressure, encompassing five studies with participants using ibuprofen for at least four weeks, revealed an SBP increase ranging from 3 to 4 mmHg.

In a more recent and extensive study involving over 400 individuals with rheumatoid arthritis (RA) or osteoarthritis (OA) using NSAIDs for four months, the blood pressure changes were compared. Most participants were concurrently using blood pressure medication. Ibuprofen, when compared to other NSAIDs like celecoxib and naproxen, resulted in a greater rise in SBP, approximately four mmHg. Notably, nearly 1 in 4 individuals developed hypertension (chronic high blood pressure) after consistent ibuprofen use over the four-month period.

These findings emphasize the need for cautious consideration, especially among individuals with pre-existing conditions or those on long-term NSAID regimens. 

What are the alternatives to Ibuprofen?

While most non-steroidal anti-inflammatory drugs (NSAIDs) have the potential to influence blood pressure, there are alternatives that individuals with high blood pressure may consider. It’s important to note that even though some alternatives may have a milder impact on blood pressure, they still share similar side effects with ibuprofen, such as kidney damage and stomach bleeding. Always consult with your healthcare provider before using any NSAIDs if you have high blood pressure.

1. Natural Alternatives to Ibuprofen

For those seeking natural alternatives to ibuprofen, various substances have shown promise in reducing inflammation. These include:

  • Turmeric
  • Green tea
  • White willow bark
  • Fish oil supplements
  • Ice for inflammation of muscles or joints

While these natural remedies may not provide immediate relief comparable to ibuprofen, they are often considered safer with fewer side effects.

2. Medical Alternatives to Ibuprofen

If you are exploring medication alternatives to ibuprofen, your medical provider may suggest:

These medications operate differently than ibuprofen and may present a better option for individuals with high blood pressure. As with any medication, discussing your health condition and potential risks with your healthcare provider is crucial to determine the most suitable alternative for your needs.

If you are facing hypertension consult a doctor now!
How many days in a row can you take ibuprofen?

The recommended duration for taking ibuprofen is ten days for adults (or three days if under 18). If you need to continue using ibuprofen beyond this period, it’s advisable to consult with your doctor before continuing. Long-term use is safe if prescribed by your doctor as long as you adhere to the recommended dosage.

Is there an anti-inflammatory that does not raise blood pressure?

If you have high blood pressure, it is important to use acetaminophen or aspirin instead of ibuprofen as they have a low chance of raising blood pressure. In addition, consider having blood pressure medications upon consultation with a doctor to keep your blood pressure in check. 

Does 200 mg ibuprofen raise blood pressure?

Ibuprofen (Advil, Motrin) has the potential to raise blood pressure, although the change is typically small. Individuals with high blood pressure or heart problems should check with their healthcare provider before taking ibuprofen. Regular use of ibuprofen can lead to potentially serious side effects, such as stomach ulcers.

Is it harmful to take two ibuprofen every day?

The current recommendation for ibuprofen is to limit daily use to 30 days. The dosage can range from 400 mg to 800 mg up to 4 times a day, with a maximum of 3200 mg daily. However, following your healthcare provider’s advice regarding the appropriate dosage and duration based on your specific health conditions is essential.

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