Treat oral thrush without a clinic visit. Get a prescription for Nystatin online.
Need quick treatment for an oral or skin infection? Skip the wait, speak to a licensed doctor online, and get a Nystatin prescription in under 5 minutes, any time, day or night. Our doctors will evaluate your symptoms and prescribe this antifungal medication at a dose that helps clear the infection quickly.

- Get Nystatin refills on your schedule
- Available in creams, tablets, oral suspension, ointments, and powder.
- Affordable flat rate, no insurance needed.
- Serving rural, urban and remote areas of Canada

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Buy Nystatin for oral thrush from your local pharmacy
Get treated for oral thrush or a yeast infection without the wait. Our seamless online care makes it easy to get a Nystatin in urban, rural, and remote areas.
Choose your local pharmacy
Select any pharmacy near your town, and we’ll send your Nystatin prescription directly.
Same-day prescription pickup
Once approved, your prescription is sent to your pharmacy within minutes, ready for pickup the same day.
Real-time prescription tracking
Get live updates from doctor approval to pharmacy confirmation from your app.
How to get your Nystatin prescription and refill online without seeing a doctor?
You can skip the office visit by talking to a doctor online through our telehealth app. You can choose to text, video, or audio chat and get your prescription without hassle within 5 minutes.
Start a consultation
Download our app, create an account, and share your infection symptoms to get started.

Speak to the doctor
Our licensed healthcare provider will review your symptoms via video, audio, or text chat to provide a diagnosis.

Get Nystatin online
If diagnosed with oral thrush, you will be prescribed Nystatin, and your online prescription will be sent to your local pharmacy.

Who can get Nystatin online?
Nystatin is an effective antifungal medication to treat yeast infections in adults and children of all ages. You may be eligible for a Nystatin online prescription if you have:
- Symptoms of oral thrush (white mouth patches and soreness)
- Signs indicating a yeast skin infection
- The risk of developing thrush after consistent antibiotic use
Dosages and Strengths of Nystatin
Nystatin is available in different strengths, and the dosage depends on the type of infection and the area being treated.
- Oral suspension: 100,000 units/mL
- Oral tablets: 500,000 units per tablet
- Topical cream/ointment: 100,000 units/g
Side Effects of Nystatin
Nystatin stays in your mouth or skin and doesn’t enter your bloodstream, so side effects are usually mild.
- Nausea or mild stomach upset
- Diarrhea
- Unpleasant taste
- Minor skin irritation or rash
- Allergic reactions (e.g., swelling, hives)
- A feeling of skin burns
If you experience severe allergic reactions accompanied by significant swelling, contact our licensed doctor online to seek medical attention immediately.
Contraindications & precautions when starting Nystatin medication
- Known allergy to Nystatin or ingredients
- Diagnosed with ringworm, athlete’s foot, or other tinea infections
- Persistent systemic symptoms like fever or widespread rash
- Rare sugar intolerance (sucrose/fructose) if using oral liquid
- Open wounds or unknown rashes
- TB of the skin or unusual infections
- No symptom improvement after 7 days of proper use
- Don’t eat or drink right after your dose
- Monitor your sugar levels during the treatment if you have diabetes
Our telehealth doctors prescribing Nystatin online

Dr. Asim Cheema
Internal Medicine
Dr. Cheema is a distinguished, board-certified Cardiology and Internal Medicine specialist who brings nearly 30+ years of extensive clinical experience to his practice. A proud graduate of Nishtar Medical College, he has been operating as an independent practitioner since 2001. He focuses on the diagnosis, management, and long-term care of complex cardiovascular and internal medicine conditions.

Dr. Marsha Dunkley
Family Medicine
Dr. Marsha Dunkley has been committed to providing compassionate, comprehensive medical care to patients across a broad spectrum of health concerns for more than five years. Her clinical experience spans both chronic conditions such as diabetes, hypertension, and high cholesterol and acute illnesses, including the common cold, seasonal allergies, influenza, and COVID-19.

Dr. Sohail Cheema
Pediatrics
Dr. Sohail Cheema is a seasoned pediatrician with 30+ years of experience. A 1987 graduate of Nishtar Medical College, he’s recognized for patient-centered care and clear communication. He's a member of the Royal College of Physicians (UK & Ireland) and certified in Ontario. He practices at Halton Healthcare – Georgetown and St. Michael’s Hospital in Toronto.

Dr. Stotland Mitchell
Occupational Medicine
Dr. Stotland Mitchell is a board-certified Occupational Medicine physician with 5+ years of experience. He provides virtual care across all U.S. states and D.C., blending allopathic medicine with public health insights. His approach focuses on rapid symptom relief and long-term prevention, often resulting in faster recovery and improved health outcomes for his patients.

Dr. Mandy Leideman
Internal Medicine
Dr. Leideman is an internal medicine physician with 30+ years of experience, currently focused on long-term care and chronic disease prevention. Known for her ethical, research-based approach, she holds certifications in human research ethics. A graduate of UWO and U of T, she completed residency at St. Joseph’s and remains active in research and professional medical organizations.

Dr. Kieran Kettyls
Family Medicine
Dr. Kieran Kettyls is a compassionate family physician specializing in bariatric medicine, women’s health, and in-office procedures. Trained in Grenada, New York, and New Jersey, he provides care including PRP, viscosupplementation, vasectomies, and cyst removals. He founded an AHS-covered weight loss program focused on sustainable outcomes and delivers personalized, results-driven care.
Frequently asked questions
What is Nystatin?
Nystatin is a powerful antifungal medication used to treat yeast infections like oral thrush, skin rashes, and intestinal Candida. It works by killing fungal cells at the site of infection without entering the bloodstream.
- Treats oral thrush in adults and infants
- Heals yeast diaper rash and skin infections
- Safe for localized Candida infections
Can I get Nystatin without over-the-counter?
No, Nystatin is a prescription medication in the United States, Canada, and elsewhere. You cannot buy Nystatin oral suspension or cream over the counter for thrush or other infections. It’s important to be evaluated by a licensed telehealth doctor, and only then will you receive a prescription. Using it without a prescription can lead to swelling and other adverse reactions.
How long does Nystatin take to work?
Nystatin starts working quickly, but the entire clearance of the infection may take several days. Many people notice improvement in symptoms after around two days of use. For example, with oral thrush, the soreness might start to get better, and the white patches may diminish after ~48 hours, but this can vary. Nystatin is prescribed for 7-14 days, and it’s important to complete your medication course.
Is Nystatin oral suspension safe to use during pregnancy?
Yes, Nystatin oral suspension (swish and swallow) is considered safe during pregnancy and breastfeeding. Since it isn’t absorbed into your bloodstream, it works only where needed and poses minimal risk to your baby. This makes it a common choice for treating oral thrush online or yeast infections during pregnancy.
Can I eat anything or drink alcohol while on Nystatin?
Since nystatin isn’t absorbed into your bloodstream, there are no food restrictions. Feel free to maintain your usual diet. Just remember to avoid eating or drinking for 30 minutes after taking the oral suspension so the medication can stay in contact with your mouth and throat. It is, however, also recommended to avoid heavy alcohol drinking as it can delay your healing process.
Does Nystatin affect birth control or fertility?
No, Nystatin does not affect contraceptive effectiveness or fertility. It’s a localized treatment and doesn’t have the systemic effects that might interfere with hormonal birth control. According to the FDA, Nystatin will not affect any type of contraception, including birth control pills, patches, implants, injections, or IUDs.
Is Nystatin an antibiotic?
No, Nystatin is not an antibiotic but an antifungal medication prescribed to treat infections caused by the growth of fungi, such as yeast. Nystatin destroys the cell membrane of fungi to stop the infection, whereas antibiotics work on bacteria.
Can I take Nystatin for ringworm?
No, Nystatin only treats yeast (Candida) infections. Ringworm is caused by dermatophyte fungi and requires a different antifungal medication. Oral thrush and ringworm can look similar, making it hard to tell them apart. That’s why it’s important to use a HIPAA- or PIPEDA-compliant telehealth service and get a proper prescription from a licensed doctor.
Is it better to spit or swallow Nystatin?
For most people, it’s better to swallow Nystatin after swishing it in the mouth. This helps treat any yeast that may be in the throat or upper digestive tract, not just the mouth. Only spit it out if your doctor specifically tells you to.
What to do if Nystatin does not work?
If your symptoms haven’t improved after 5 to 7 days of using Nystatin as directed, it may not be the right treatment for your infection. Some types of yeast, such as those from Candida glabrata, don’t respond well to Nystatin. In other cases, the infection might not be fungal at all. Don’t worry, as this is common, and we can help. Simply start a follow-up chat with our doctor. We may prescribe a more potent antifungal, like fluconazole, or recommend a lab requisition.
How can I get a Nystatin prescription for my children with thrush online?
You can get a Nystatin prescription for your child of 6 years or more through a quick telehealth visit with one of our licensed doctors. You’ll answer a few questions about your child’s symptoms and may be asked to upload a photo of the affected area (like the tongue or cheeks). If the doctor confirms oral thrush, they’ll send a Nystatin prescription directly to your pharmacy.
How much does Nystatin cost without insurance?
Nystatin oral suspension costs around $10–$25 in the US without insurance, while in Canada, it ranges from $15–$30 CAD, depending on the pharmacy and location. Prices also vary based on the form (liquid, cream, tablet) and your chosen pharmacy. Your Doctors Online is a private service, so you don’t need insurance to get a prescription. We also offer a family-sharing model, so you can cover multiple family members under one account, making care more affordable.
Nystatin vs fluconazole for thrush, which is better?
Nystatin is usually the first choice for mild oral thrush, especially in infants, because it works locally and isn’t absorbed into the bloodstream. Fluconazole, taken as a pill, is better for moderate or recurring infections since it works throughout the body. Your healthcare provider will decide the best medication based on your symptoms and health needs.
What are alternatives to Nystatin if I'm allergic to it?
If you’re allergic to Nystatin, your doctor may issue another antifungal medication online prescription, such as:
Depending on the type and location of your infection. These medications are commonly used for thrush, skin, or vaginal yeast infections and can be safely prescribed online.
How do I use Nystatin tablets?
Here are a few guidelines to follow when you are taking Nystatin tablets:
- Swallow the tablet whole with a glass of water
- Do not chew or crush it.
Take the tablet exactly as prescribed, usually 1–2 times daily, depending on your doctor’s instructions. It is important to note that Nyatatin tablets are not.
What are Nystatin lozenges?
Nystatin lozenges (pastilles) are small tablets that dissolve slowly in your mouth to treat oral thrush. As they dissolve, the medication coats your mouth and throat to kill the yeast. They’re an alternative to the liquid form and are usually taken 3 to 5 times daily as prescribed.