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Get a prescription for Nitroglycerin ointment online

Nitroglycerin is a medication prescribed to treat and manage moderate to severe pain caused by chronic anal fissures, which are small tears in the skin around the opening of the anus. 

Getting a Nitroglycerin prescription from us is straightforward and effortless; you can connect with a qualified doctor anytime through “Your Doctors Online” to discuss your presenting symptoms. However, a Nitroglycerin prescription will only be provided after consultation with our qualified doctor and if the treatment is entirely safe and suitable for you.

What is Nitroglycerin ointment?

Nitroglycerin ointment belongs to the pharmacological class of drugs known as nitrates. Nitrates are vasodilators that dilate (widen) blood vessels, particularly veins and arteries. It is commonly prescribed for angina but is also used for anal fissures and erectile dysfunction by relaxing muscles and improving blood flow, with caution due to potential side effects.
Nitroglycerin is available in various compositions, including ointments, patches, and sublingual tablets, and it should only be taken with the doctor’s prescription.

Uses of Nitroglycerin

Nitroglycerin is used to prevent and treat chest pain (angina) in people who are suffering from coronary artery disease. Nitroglycerin is also used in certain situations to help manage heart failure, control blood pressure during surgery, and treat certain types of heart attacks. Ointments and nitroglycerine cream or nitroglycerine ointment may be used to help with symptoms of anal fissures and erectile dysfunction (ED).

How does Nitroglycerin work?

Nitroglycerin releases nitric oxide, which relaxes and dilates blood vessels by affecting the smooth muscles, increasing blood flow. In angina, it widens coronary arteries, improving oxygen supply to the heart. For anal fissures, it relaxes the anal sphincter muscle, aiding healing. In erectile dysfunction, it enhances penile blood flow, facilitating erection.

What are the different dosage forms and strengths of Nitroglycerin?

Nitroglycerin is available in four different dosage forms and strengths, including sublingual tablets, sublingual sprays, oral tablets, transdermal patches, and ointment. Common concentrations for ointments include 2% and 0.2%, while patches typically come in strengths ranging from 0.1 mg/hour to 0.8 mg/hour. Sublingual tablets may be available in doses such as 0.3 mg, 0.4 mg, or 0.6 mg.

How to take it?

Nitroglycerin can be taken sublingually as tablets or spray, with tablets placed under the tongue to dissolve and spray administered under the tongue. Oral tablets should be swallowed whole with water, and transdermal patches should be applied to clean, dry, hairless skin. The ointment should be applied thinly to the affected area.

Side effects of Nitroglycerin

Common side effects:

  • Headache
  • Dizziness
  • Lightheadedness
  • Flushing
  • Burning sensation under the tongue (sublingual use)

Serious side effects:

  • Severe drop in blood pressure
  •  Dizziness
  •  Fainting
  •  Rapid heartbeat
  •  Methemoglobinemia
  •  Bluish tint to the skin
  •  Confusion
  •  Dizziness
  •  Shortness of breath

Request Nitroglycerin prescription online

Get an online prescription for Nitroglycerin in three easy steps.


Describe your issue

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  • Angina
  • Anemia
  • STD
  • UTI
  • Skin
  • Covid


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Hi I’m Dr. Nicole. How may I help you?

Hi Dr. Nicole, I have a rectal bleed and anal fissures. Can I get some form of treatment, please?


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  • Nitroglycerin sublingual tablet 0.4 mg daily.



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Precautions and Contraindications

  • Be cautious when handling machinery or driving since nitroglycerin can make you lightheaded or dizzy. 
  • Avoid sudden changes in position, as this can lead to a drop in blood pressure.
  • Do not take nitroglycerin or its ingredients if you are allergic to it.
  • Do not take erectile dysfunction medications (e.g., sildenafil, tadalafil, vardenafil) with nitroglycerin, as this can cause a severe drop in blood pressure.
  • Do not use nitroglycerin if you have severe anemia, increased pressure in the head, or certain types of heart conditions (e.g., hypertrophic cardiomyopathy or constrictive pericarditis).

FAQs about Nitroglycerin prescription online

Do you need a prescription for Nitroglycerin ointment?

Yes. It is a prescription medication used to treat certain medical conditions, such as angina and chronic anal fissures, and should only be used under the guidance of a healthcare provider.You can get nitroglycerine gel/cream prescriptions online via telemedicine platforms.

Can Nitroglycerin kill you?

Yes, if nitroglycerin is not used correctly, it can be lethal. An extreme reduction in blood pressure brought on by an overabundance of nitroglycerin can result in fainting, shock, or even death. 

How to apply Nitroglycerin ointment for fissures?

Gently slide the ointment-covered finger into the anal canal. Never extend your finger beyond the first joint. Apply the ointment to the inner walls of the anal canal with caution. Apply the ointment straight to the outside skin if the anal canal is causing you too much agony. 

What are the alternatives to Nitroglycerin ointment?

Alternative treatments for anal fissures include topical calcium channel blockers (e.g., diltiazem) and botulinum toxin injections. Dietary changes, stool softeners, and fibre supplements can also help improve symptoms and promote healing. Surgical procedures may be considered for chronic or severe cases.

What to avoid with Nitroglycerin ointment?

If you take vardenafil (Levitra®), tadalafil (Cialis®), sildenafil (Viagra®), or riociguat (Adempas®), do not use this medication. When using one of these medications while taking nitroglycerin, side effects could include sharp drops in blood pressure, blurred vision, lightheadedness, dizziness, or fainting.

How do you know if Nitroglycerin is working?

It would help if you experienced relief from angina five minutes after taking your first nitroglycerin dose. You may take one nitroglycerin dosage every five minutes for a maximum of three doses.

How long does Nitroglycerin last after you take it?

Nitroglycerin usually takes 1 to 5 minutes to start working. You might need to take this drug three to four times a day because its effects continue for about five hours.

Your Doctors Online uses high-quality and trustworthy sources to ensure content accuracy and reliability. We rely on peer-reviewed studies, academic research institutions and medical associations to provide up-to-date and evidence-based information to the users.

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