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Get a prescription refill for Rifaximin (Xifaxan) online

Rifaximin is an antibiotic class of medications prescribed to treat irritable bowel syndrome (IBS-D), hepatic encephalopathy, and traveler’s diarrhea. 

If you have the above-mentioned conditions, including IB-D, GIT, and hepatic encephalopathy, you can get a Rifaximin refill online within minutes. Please note that a Rifaximin refill will only be provided after consultation when you briefly describe your symptoms. Prescription refill will only be provided if the medication is appropriate and safe for your unique needs.

What is Rifaximin?

Rifaximin is an antibiotic containing Rifamycin as an active ingredient. It mainly treats gastrointestinal diseases, including traveler’s diarrhea or IBS. It is available as Xifaxan tablets with different dosage strengths prescribed depending on the nature and severity of the medical condition. It is also considered a broad-spectrum antibiotic that treats several bacterial infections.

What are the uses of Rifaximin?

Rifaximin is used for a number of medical conditions associated with the gastro-intestinal tract. Some prominent uses of rifaximin include: 

  • Prevention of hepatic encephalopathy in patients with liver disease.
  • Irritable bowel syndrome with diarrhea (IBS-D)
  • Treating small intestinal bacterial overgrowth (SIBO)
  • Clostridium difficile-associated diarrhea (off-label use)
  • Traveler’s diarrhea is caused by Escherichia coli (bacteria) 

How does it work?

The exact mechanism of action is not known, but Rifaximin acts locally in the gut. It is a gastrointestinal-specific antibiotic. It inhibits bacterial RNA synthesis by binding to the beta subunit of the bacterial DNA, thus relieving symptoms of irritable bowel syndrome and leading to improved gut health.

What are the different dosage forms and strengths of Rifaximin?

Rifaximin is only available in  oral tablet dosage form: 

  • Tablets have two strengths, including 200mg and 550mg. 

How to take it?

For effective treatment options, oral tablets should be taken with water or without food. Do not chew or crush the tablet. The medication should be taken according to the frequency prescribed by your healthcare provider. 

What are the side effects of Rifaximin?

Some of the most common side effects of Rifaximin are: 

  • Nausea
  • Flatulence
  • Headache
  • Dizziness
  • Abdominal pain
  • Bloating

Some severe side effects are: 

  • Allergic reactions
  • Severe diarrhea
  • Liver problems
  • Severe abdominal pain
  • Swelling of the ankles or feet (rare) 

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Hi I’m Dr. Nicole. How may I help you?

Dr. Nicole, I have been taking Rifaximin for irritable bowel syndrome. Can you give me a Rifaximin refill?


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  • Rifaximin 400 mg tablet
  • Take one tablet thrice daily for 2 weeks


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Precautions and contraindications

  • Share your medication history with your healthcare provider to avoid any allergic reaction. 
  • This medication is safe to be used in pregnancy and won’t harm the mother or developing baby. It’s still beneficial to discuss any medicines before taking pregnancy with your doctor to avoid any unwanted side effects. 
  • In case of any liver problem, discuss it with your doctor before getting the prescription. 

FAQs about Rifaximin refill

What is the typical starting dose of Rifaximin (Xifaxan)?

For irritable bowel syndrome, the recommended daily dose for adults is 550 mg daily. Do not overdose or underdose the recommended dose and follow the exact dosing schedule recommended by your doctor.

Can I get Rifaximin (Xifaxan) over the counter?

No, it is a prescription medication not available for use over the counter. You will need a prescription from your health care provider to purchase it from a pharmacy.

When is the best time to take Rifaximin?

It is recommended to take Rifaximin thrice daily at a dosing interval of 8 hours each. This means you should take it in the morning, noon, and evening. However, your doctor may prescribe it according to your individual needs.

Who should not take Rifaximin?

People hypersensitive to Rifamycin antibiotics or any Rifamixin ingredients should avoid taking it. People with bloody diarrhea or taking medications contraindicated with Rifaximin should avoid it.

What happens if I miss a dose of Rifaximin?

If you happen to forget a dose, make an effort to take it as soon as you recall. If it is time for your next dose, it is recommended to skip the previous dose and only take your next scheduled dose.

What happens if I take too much Rifaximin?

If you overdose on Rifaximin, you may experience an increased risk of side effects that may worsen, including stomach pain, fever, fluid buildup, and watery or bloody diarrhea.

What are the alternatives to Xifaxan?

Some of the best alternatives to Xifaxan are ciprofloxacin or azithromycin, which are recommended by healthcare providers for the treatment of travelers' diarrhea and IBD.

How long do Xifaxan side effects last?

Side effects of Xifaxan can last from a couple of days to a few weeks, depending on the dose you are taking and for how long it is prescribed. In case of persistent side effects, it's better to consult a healthcare provider.

What to avoid while taking Xifaxan?

There are no specific guidelines about avoiding some specific things while taking Xifixan. However, Alcohol consumption should be avoided in any case to avoid any medical complexities.

Can you take Rifaximin and Neomycin together?

No. They are usually not prescribed to take rifaximin and neomycin together. It is always recommended to have 2 hours gap between both the medications to avoid any interactions, and optimum time is given for the absorption.

Should I take a probiotic while taking Xifaxan?

No, It's important to discuss it with your doctor before taking any probiotic or supplemental against when taking medications to avoid drug interactions and absorption issues.

Does Rifaximin kill good bacteria?

No, it only kills the pathogenic bacteria in the gut, and it has shown an overall good impact on the gut microbiota. It, however, does kill some of the gut bacteria, but the overall composition of gut bacteria does not change.

How does Rifaximin work for hepatic encephalopathy?

Rifaximin decreases the concentration of pro-inflammatory cytokines by reducing the concentration of toxins derived by the gut. The exact mechanism of action of Rifaximin against hepatic encephalopathy is not known.

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