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Get a prescription refill for Estradiol online

Estradiol is used for contraception and hormone replacement therapy to treat menopause and osteoporosis. Estradiol is a medication prescribed to treat and manage menopause symptoms and bone health.

Getting an Estradiol prescription from us is straightforward and effortless; you can connect with a qualified doctor anytime through “Your Doctors Online” to discuss your presenting symptoms. However, an Estradiol prescription will only be provided after consultation with our qualified doctor and if the treatment is entirely safe for your unique needs.

What is Estradiol?

Estradiol treats gynecological conditions, hormone-sensitive cancers, osteoporosis, and delayed puberty with gender-affirming hormone therapy. Estradiol is a female hormone medication. This medication is also recommended to treat bone loss after menopause. This medication is prescribed for those unable to produce this hormone naturally.

Uses of Estradiol

Estradiol is responsible for the management of menopause symptoms, including hot flashes, vaginal itching, and dryness.

How does it works?

Estradiol works as the natural hormone replacement in the body that functions instead of the natural hormones that the body should produce. It is recommended to treat and manage extreme menopause symptoms, including hot flashes, mood swings, and bone loss.

What are the different dosage forms and strengths of Estradiol?

Estradiol is available in different dosage forms and strengths, including injections (5mg/mL,10mg/mL,20mg/mL,40mg/mL), patches, creams, gels (0.06%,0.1% ), vaginal rings, and oral tablets (0.45mg,0.5mg,0.9mg,1mg,1.5mg,2mg).

How to take it?

Estradiol’s dosing schedule differs from one dosage form to the next. Transdermal patches are typically changed every few days, while oral tablets can be taken once daily. Dosing for topical products like creams, gels, and vaginal rings can vary. Following the prescribed dosage and dosing instructions is beneficial for maximum effectiveness.

Side effects of Estradiol

Common side effects Include:  

  • Nausea
  • Breast tenderness
  • Headache
  • Fluid retention

Serious side effects are: 

  • Blood clots
  • Stroke
  • Heart attack
  • Some forms of cancer

Request Estradiol prescription refill

Get a prescription refill for Estradiol in three easy steps.


Describe your issue

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Hi I’m Dr. Nicole. How may I help you?

Dr. Nicole, I have Osteoporosis; I feel better after taking Estradiol. Can you give me an Estradiol refill?


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Our online doctors can help you with your medical issues and give you prescriptions.


  • Estradiol 1 mg tablet,
  • Take one tablet once daily.

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Prevention and ContraIndications

  • Discuss your medication history with your healthcare provider to avoid any interactions. 
  • Follow the dose and dosage instructions as provided by your healthcare provider and pharmacist. 
  • In case of any vaginal bleeding, talk to your healthcare provider immediately to avoid any infection in the uterus. 
  • This medication is recommended to be used at the lowest effective dose for the shortest time to avoid side effects. Consult your healthcare provider for any dosing and duration-related queries. 

FAQs about Estradiol prescription refill

Can you get Estradiol over the counter?

No, in order to obtain Estradiol, a prescription from a qualified healthcare provider is necessary. This requirement ensures that individuals who are prescribed Estradiol receive appropriate medical guidance and supervision throughout their treatment journey.

How long does it take for Estradiol to work?

The onset of action for Estradiol oral tablets is about 2-4 weeks. The time it takes for a medication to start working can vary based on factors such as the specific dosage form being used and how an individual’s body responds to the medication. It is possible to experience relief from menopause symptoms within a few weeks of initiating treatment.

What is the typical starting dose of Estradiol?

Starting doses typically fall within the 1-2 mg per day range. The diagnosis and dosage form will determine the initial dose. For specific dosing advice, please speak with your healthcare provider.

Who should not take Estradiol?

Estradiol should generally be avoided by people who have had certain types of cancer, blood clots, liver disease, or uncontrolled hypertension in the past. If it’s safe for you to do so, your doctor will tell you.

What happens if I miss a dose of Estradiol?

It is crucial to adhere to the instructions provided by your healthcare provider. By doing so, you are ensuring that you are receiving the most effective and appropriate care for your specific health needs. Your healthcare provider possesses the knowledge and expertise to guide you toward optimal health outcomes.

What happens if I take too much Estradiol?

It is important to be aware that consuming an excessive amount of Estradiol can result in the manifestation of overdose symptoms. These symptoms may include but are not limited to nausea, vomiting, and vaginal bleeding. Therefore, it is crucial to adhere to the prescribed dosage and consult with a healthcare professional if any concerns or questions arise regarding the appropriate usage of this medication.

Is this an FDA-approved medication?

Yes. Estradiol is an FDA-approved medication with multiple dosage formulations for the management of menopause symptoms and bone loss therapy. 

Which medicine should be avoided with Estradiol?

Some drugs that can interact with this drug include aromatase inhibitors (such as anastrozole, exemestane, and letrozole), fezolinetant, fulvestrant, ospemifene, raloxifene, tamoxifen, and tranexamic acid.

Your Doctors Online uses high-quality and trustworthy sources to ensure content accuracy and reliability. We rely on peer-reviewed studies, academic research institutions and medical associations to provide up-to-date and evidence-based information to the users.

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