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Antinausea medications are available over-the-counter as well as upon prescription. Get a prescription for your condition from our online doctors within minutes of consultation.
From prescription to over-the-counter antiemetics, our board-certified doctors are here to help you find the best antinausea medicine for your medical condition within minutes.
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Controlled substances policyAbout anti-nausea medications
Anti-nausea medications, also known as antiemetics, can treat symptoms like morning sickness, nausea, and vomiting. These symptoms can be the result of various health conditions and medications, including pregnancy, chemotherapy, opioid medications, and certain underlying health conditions and therapies. It is a reflex action of the body towards certain toxic substances in the gut. However, antiemetics can help reverse or suppress these symptoms effectively.
What conditions does antinausea treat?
Antinausea can help treat the feelings of vomiting and nausea caused by an infection, motion sickness, food poisoning, gastroenteritis, upper abdominal irritations, and hormonal changes during pregnancy, including its extreme condition called hyperemesis gravidarum. In any case, and especially during pregnancy, do not take antiemetics during pregnancy without consultation from a doctor.
Types of antiemetics
Antiemetic drugs come in different formulations, from oral solutions to sublingual tablets, suppositories, transdermal patches, and intravenous injections. Depending on the receptor they act, antinausea medications are divided into several classes, including the following:
Dopamine antagonists
They are used for postoperative nausea and motion sickness, for example:
- Metoclopramide (Reglan)
- Domperidone (Motilium)
- Chlorpromazine
5-HT3 receptor antagonists
These medications work on the central and peripheral serotonin receptors in the vomiting center and the vagus nerve, respectively. They are prescribed for acute gastroenteritis, chemotherapy-induced nausea, and postoperative nausea, for example:
- Ondansetron (Zofran)
- Granisetron
- Palonosetron (2nd generation)
H1 antihistamines
This class of antiemetics is used to treat vertigo-related nausea or motion sickness due to vestibular disturbances, for example:
- Cyclizine
- Promethazine
- Diphenhydramine
- Anticholinergics like scopolamine
Neurokinin 1 (NK-1) receptor antagonists
It is a relatively new antiemetic class used to treat radiotherapy and chemotherapy-induced nausea and vomiting post-surgery. However, it is not recommended for pregnant or breastfeeding women. Examples include:
- Aprepitant (Emend)
- Rolapitant (Varubi)
Glucocorticoids
Glucocorticoids are also used against postoperative nausea and vomiting related to chemotherapy emesis. It works fine, but some side effects include insomnia, energy, and mood swings.
Consult a doctor to choose the most appropriate antinausea medicine for your condition with the least side effects and the highest efficacy.
How does antinausea work?
Antinausea medicine works by blocking the receptors involved in vomiting-related neural pathways. These receptors respond to certain neurotransmitters, such as dopamine, serotonin, and histamine, inducing vomit or nausea. Upon receiving the threat signal, the gastrointestinal tract sends the information to the peripheral receptors and the vomiting center, stimulating nausea and vomiting by triggering abdominal muscles and the diaphragm.
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1
Describe your issue
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- Morning Sickness
- Anemia
- STD
- UTI
- Skin
- Covid
2
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Dr. Nicole, I have cold and flu-like symptoms. Can you give me something to help relieve these symptoms ?
3
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Prescription
- Ondansetron, 8mg, thrice a day, 7 days.
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Side effects of antinausea medicines
Some of the severe and rare side effects of antivirals include:
- Anemia
- Hives
- Itching on body
- Rashes
- Increased liver enzymes
- Hoarseness
- Wheezing
- Tightness in the chest
Whether prescription or over-the-counter antiemetics, consult a doctor to get a prescription for the appropriate class of antiemetics for your condition. Also, to avoid the interactions of antinausea medications with other medications you might be having, see a doctor.
Risks of antinausea medications
If you have a certain medical condition or are allergic to any active ingredient, you should consult a doctor for the right antiemetics. Usually, the following people should avoid using antiemetics in general:
If you are allergic to salicylate medicines like aspirin, or avoid giving bismuth subsalicylate to children under 12.
In case of chickenpox or flu, avoid giving your child antinausea medication as it increases the risk of Reye’s Syndrome, which causes liver and brain swelling.
If you take blood thinners or prescription medications for arthritis, diabetes, and gout, consult a doctor before taking antiemetic medicine.
FAQs about antinausea medications
What is the best prescription medicine for nausea?
One of the most effective nausea medications available upon prescription include ondansetron, granisetron, and palonosetron from the class 5-HT3 receptor antagonists. They block the serotonin receptor in the gut and brain to stop vomiting and nausea signals. They are prescribed to patients having chemotherapy.
What is the new anti-nausea medication?
New antinausea medications approved by the FDA include aprepitant and palonosetron for treating nausea and vomiting.
What is the prescription for anxiety nausea?
For the treatment of anxiety and nausea in mental health conditions like schizophrenia and non-psychotic anxiety, prochlorperazine can be prescribed for controlling severe nausea and vomiting.
What can I take for instant nausea relief?
You can get instant relief from nausea and vomiting by taking antiemetics from the class of dopamine receptor antagonists like metoclopramide and prochlorperazine. However, consulting a doctor for your medical condition and body suitability is better.
What can doctors prescribe for nausea during pregnancy?
Doctors can prescribe doxylamine pyridoxine for the treatment of nausea during pregnancy. However, if it doesn’t improve the symptoms, your doctor may prescribe a combination of doxylamine-pyridoxine.
What anti-nausea medicine causes birth defects?
Some of the antinausea medicines like thalidomide, if taken during pregnancy for the treatment of morning sickness, can cause birth defects like deformed limbs and organs, as per one research. Therefore, it is mandatory to consult a doctor before taking any antiemetic during pregnancy.
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