Overview
When it comes to managing hemorrhoids, prescription medications can provide powerful relief, especially for those who have found over-the-counter options insufficient. Hemorrhoids, swollen veins in the rectal and anal areas, can lead to discomfort, itching, and even significant pain. Prescription treatments often include more potent formulations that target inflammation, reduce swelling, and provide fast-acting pain relief.
This blog will explore the top prescription options available, how they work, and why they might be the best choice for long-term relief from hemorrhoid symptoms.
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Instant ConsultationIs there a prescription medicine for hemorrhoids?
Hemorrhoids are a common condition, with about half experiencing them by age 50. Despite their prevalence, many people feel uncomfortable seeking treatment. While home remedies can ease symptoms, prescription treatments are often needed for effective relief.
There are several prescription medications available for hemorrhoids, classified into oral and topical options based on how they are administered. These medications are typically used when over-the-counter remedies are ineffective.
Topical Prescription Medications for Hemorrhoids
- Corticosteroid Creams and Suppositories:
- Hydrocortisone Creams (e.g., Anusol-HC, Proctocort) is one of the best hemorrhoid creams available.
- Analpram HC (combines hydrocortisone and pramoxine)
- Proctofoam HC (foam formulation for easier application)
- Nitroglycerin Ointment:
- Used to relieve anal fissures and hemorrhoid-related pain by relaxing anal muscles, reducing sphincter pressure.
- Calcium Channel Blocker Ointments:
- Nifedipine Ointment (also relaxes the anal sphincter, reducing pain and promoting healing) is a prescription hemorrhoid cream.
- Local Anesthetics:
- Lidocaine Cream (numbs the area, providing temporary pain relief)
- Pramoxine Ointment (often combined with corticosteroids for enhanced relief)
Oral Prescription Medications for Hemorrhoids
- Pain Relievers:
- Laxatives:
- Lactulose and polyethylene Glycol (MiraLAX)—while not specifically for hemorrhoids, these may be prescribed to relieve constipation and prevent strain on hemorrhoids.
Stool Softeners
- Prescription stool softeners like Docusate Sodium (Colace) may be given to help prevent straining, which is crucial in managing and preventing further irritation or worsening of hemorrhoids.
These medications should be used under a healthcare provider’s supervision. Some, especially corticosteroids, should only be used for a limited duration to avoid side effects like skin thinning or increased sensitivity in the affected area.
Research says: Married, pregnant women with excess weight and low-fiber diets have a higher risk of hemorrhoids. Complications are preventable if treated at an early stage.
“Hemorrhoids are a widespread issue that many people hesitate to address, often delaying necessary care. Early treatment can offer substantial relief and help prevent the condition from worsening to needing surgery. Addressing hemorrhoid symptoms promptly can greatly improve both comfort and daily well-being.”
What is the best and most potent prescription medicine for hemorrhoids?
Here is a table of the most potent and best prescription medications for treating hemorrhoids available in the U.S. and Canada:
| Drug | Dose | Role and Precautions | Availability in the U.S. | Availability in Canada |
| Corticosteroids, topical | ||||
| Hydrocortisone rectal suppository (25-30 mg) | One suppository per rectum up to 2 times/day | Local anti-inflammatory effect; short-term use recommended | Prescription (higher strengths) | Prescription |
| Vasoactive agents, topical | ||||
| Nitroglycerin (glyceryl trinitrate) 0.2-0.5% ointment | Apply pea-sized amount 2 times/day | Manages pain associated with anal sphincter spasm or thrombosed hemorrhoids; systemic side effects common | Prescription | Prescription |
| Combination of anesthetic and corticosteroid, topical | ||||
| Lidocaine and hydrocortisone cream/gel (e.g., lidocaine-hydrocortisone 2%-2%, 3%-0.5%, 3%-1%) | Apply as needed up to 2 times/day. | Temporary relief of pain and pruritus; local anti-inflammatory effect; short-term use recommended | Prescription | Prescription |
Note:
These medications generally require a prescription due to the potency of active ingredients.
What is the best prescription medicine for internal hemorrhoids?
For Pain and Itching:
Hydrocortisone Suppositories or Rectal Cream (25-30 mg suppositories or 1-2.5% cream): These provide anti-inflammatory relief and reduce itching and swelling. They’re recommended for short-term use (up to 7 days) to avoid mucosal thinning.
For Bleeding and Swelling:
Oral Flavonoids (like Daflon, where available): Diosmin and hesperidin can reduce bleeding and inflammation. A prescription may be required, though Daflon is unavailable in the U.S. and Canada.
Phenylephrine (e.g., Preparation-H): This topical vasoconstrictor is used in suppository form to reduce bleeding and swelling.
For Pain from Sphincter Spasm:
Nitroglycerin Ointment (0.2-0.5%): Helps alleviate pain associated with anal sphincter spasms and thrombosed hemorrhoids.
Severe hemorrhoids may lead to thrombosis, prolapse, or infection, which can require more invasive treatments or surgery if left untreated.
Is there a pill that gets rid of hemorrhoids?
Yes, Daflon is a vasoactive medication pill containing a micronized purified flavonoid fraction, primarily composed of diosmin and hesperidin. It’s commonly prescribed to treat symptoms associated with chronic venous insufficiency and hemorrhoidal disease. However, its use is limited according to FDA-approved guidelines.
When should you consult a doctor for hemorrhoid treatment?
Consult a doctor for hemorrhoid treatment if:
- Bleeding persists or worsens
- Severe pain occurs, especially with thrombosed hemorrhoids
- Symptoms don’t improve after one week of OTC treatments
- There’s noticeable swelling or prolapse
- You experience frequent recurrences
- You have changes in bowel habits or significant weight loss
FAQs about prescription medicine for hemorrhoids
To shrink hemorrhoids quickly, start home treatments as soon as you notice symptoms. Combining warm sitz baths, witch hazel, and over-the-counter hemorrhoid creams can effectively soothe discomfort and reduce inflammation before it worsens. These remedies help relieve itching, pain, and swelling, promoting faster healing. Acting early can prevent hemorrhoids from becoming more irritated.
The best over-the-counter treatment for hemorrhoids typically includes a combination of soothing creams, cooling pads, and anti-inflammatory options. Hydrocortisone creams reduce itching and swelling, witch hazel pads relieve irritation, and topical anesthetics, like those in Preparation-H, help alleviate pain. For optimal relief, consider pairing these with a warm sitz bath to promote healing and ease symptoms effectively.
Treatment for a thrombosed hemorrhoid depends on how soon it’s addressed. Surgical clot removal within the first 24–48 hours can provide rapid relief. After 48 48-hour window, conservative measures are recommended, including over-the-counter pain relievers, warm sitz baths to reduce pain and swelling, topical hydrocortisone or anesthetic creams, and cold compresses. Increasing fiber and fluid intake can also help reduce straining. For persistent or severe symptoms, consulting a healthcare provider is essential.
For severe hemorrhoids, doctors may recommend:
1. Prescription Creams/Ointments: Steroid-based for pain and inflammation.
2. Pain Relievers: OTC options like acetaminophen or ibuprofen.
3. Minimally Invasive Procedures:
Rubber Band Ligation: Cuts off blood supply to hemorrhoid.
Sclerotherapy: Injection to shrink hemorrhoid.
Coagulation Therapy: Uses heat or light to shrink tissue.
4. Surgery: Hemorrhoidectomy or stapling for severe cases.
5. Lifestyle Changes: High-fiber diet, hydration, and avoiding straining
To apply the hemorrhoid ointment, the patient can sit or lie down, gently insert the medicine with a finger about 1-2 cm into the anus, and allow it to dry for 5–20 minutes. Dispose of gloves and close the tube tightly after use. Apply twice daily, in the morning and evening.
Hemorrhoid cream works by numbing the area to relieve pain, reducing inflammation to decrease swelling, and constricting blood vessels to minimize discomfort and shrink the tissue.
