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Get Methotrexate prescription refill online

Methotrexate is a medication used to treat rheumatoid arthritis, psoriasis, and some sorts of cancer. If you have these conditions, you can refill Methotrexate online. Our online doctor will ask about your symptoms to determine treatment.

Please know that a Methotrexate refill will only be provided after a consultation with our doctor and if the medication is appropriate and safe.

What is Methotrexate?

Methotrexate is an antimetabolite. Cancers like leukemia, breast cancer, and lung cancer are the most common ones for which it is prescribed. In addition, it is commonly used to treat psoriasis and rheumatoid arthritis in low doses, both of which are autoimmune diseases.

Uses of Methotrexate

Methotrexate is useful in treating many types of cancer because it inhibits or completely halts the growth of cancer cells. It reduces inflammation in conditions like rheumatoid arthritis and psoriasis.

How does it work?

Methotrexate is effective because it prevents the breakdown of folic acid, a B vitamin necessary for cell division and growth. When used to treat cancer, this method inhibits the spread of cancer. Methotrexate also helps reduce inflammation and an overactive immune response in autoimmune diseases.

How to take Methotrexate?

Methotrexate can be taken orally or intravenously. It’s important to take your medication exactly as prescribed by your doctor. In the case of autoimmune disorders, it is typically administered once weekly rather than daily.

Side effects of Methotrexate

Common side effects include: 

  • Nausea
  • Fatigue
  • Mouth sores

More severe side effects can involve: 

  • Liver damage
  • Lung problems
  • Decreased blood cells
  • Increased infection risk

Request Methotrexate prescription refill

Get a prescription refill for Methotrexate online in three easy steps.


Describe your issue

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  • Rheumatoid arthritis
  • Anemia
  • STD
  • UTI
  • Skin
  • Covid


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Hi I’m Dr. Nicole. How may I help you?

Dr. Nicole, I’ve been experiencing joint pain and stiffness lately, especially in the mornings. Can you give me a Methotrexate refill?


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Our online doctors can help you with your medical issues and give you prescriptions.


  • Methotrexate 7.5mg tablet; take one tablet once a week.



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Precautions and contraindications

  • It is not recommended to use Methotrexate during pregnancy as it can cause birth defects in the fetus.
  • Methotrexate’s side effects on the liver may be exacerbated by alcohol consumption.
  • You should get regular blood tests to monitor your liver health and blood cell counts.
  • Voltaren (diclofenac topical), Rexaphenac, Flector, Celebrex (celecoxib), Pennsaid, Solaraze, Tylenol, and Paracetamol (acetaminophen) can have possible drug interactions with Methotrexate.

FAQs about Methotrexate prescription online

Is it safe to take Viagra with Methotrexate?

Taking methotrexate and Viagra at the same time is not advised due to an interaction between the two drugs.

Can Methotrexate cause weight gain?

Yes, Methotrexate may cause weight gain in some people. However, the increase in weight is typically not too severe.

How to boost the immune system while taking Methotrexate?

Managing stress, getting enough sleep, and eating well are all important factors. Proteins, carbohydrates, healthy fats, vitamins, and minerals are important components of the diet and should be consumed in a balanced proportion. Taking folic acid while on methotrexate is important as well. Talk to your doctor to find out the recommended dosage of folic acid for you.

How long does Methotrexate stay in your system?

The effects of Methotrexate, even after treatment has been stopped, can linger for weeks or even months. It is crucial to know this fact to properly manage any potential interactions or side effects during this post-medication phase.

How long does it take for Methotrexate to work?

This question is condition-specific. However, it may take a considerable amount of time, anywhere from a few weeks to a few months, to fully impart the desired effects, especially in the case of autoimmune diseases.

Does Methotrexate cause hair loss?

Yes, this is a common side effect. Those who take higher doses usually experience hair loss. Discuss with your doctor if you are facing this side effect and are worried about it.

What are the alternatives for Methotrexate?

Depending on your condition, alternatives may include other disease-modifying antirheumatic drugs (DMARDs), biologics, or targeted synthetic DMARDs.

Your Doctors Online uses high-quality and trustworthy sources to ensure content accuracy and reliability. We rely on peer-reviewed studies, academic research institutions and medical associations to provide up-to-date and evidence-based information to the users.

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